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It is important to be aware of the safety information related to the use of this medication. The following points outline potential risks and necessary precautions to ensure safe and effective use. If you have any questions or concerns, please consult your healthcare provider.

• Hormonal Changes: Excessive absorption of topical steroids like alclometasone through the skin may disrupt your body's natural stress hormone levels, potentially leading to increased blood sugar or easier bruising. Though this is uncommon with alclometasone due to its low potency, the risk increases with prolonged use or application over large skin areas. To minimize this risk, healthcare providers will prescribe the smallest effective dose for the shortest duration. Factors that increase the risk include using multiple topical steroids concurrently, extended use of alclometasone, applying excessive amounts, covering treated areas, and use in young children.

• Skin Infections: Alclometasone can reduce your skin's infection-fighting capabilities. It is crucial to manage any existing skin infections with suitable antifungal or antibacterial treatments while using this medication. Discontinue use and contact your healthcare provider immediately if you experience redness, pain, swelling, or pus at the application site.

• Skin Irritation: Extended use of alclometasone or applying more than the recommended dose can lead to skin reactions such as thinning, stretch marks, burning, itching, irritation, dryness, or rash. To avoid severe reactions, your healthcare provider will prescribe the minimum effective dose for the shortest necessary treatment period. Report any new or worsening skin conditions to your healthcare team promptly. The risk of skin irritation increases with higher doses and longer usage periods.

There are no known contraindications for alclometasone. Always follow your healthcare provider's instructions and seek guidance if you have any questions regarding the use of this medication.

Common side effects:

• stinging
• burning
• itching
• irritation
• dryness
• redness of the skin

Less common but important to monitor:

• small red itchy bumps
• skin redness

Serious side effects:

• skin thinning
• discoloration
• acne
• unwanted hair growth
• folliculitis
• unusual tiredness
• weight loss
• headaches
• swelling of ankles/feet
• increased thirst
• increased urination
• vision problems
• rash
• severe dizziness
• difficulty breathing

Alclometasone is a topical corticosteroid used to treat various skin conditions. While it is generally applied to the skin and has minimal systemic absorption, there are potential interactions to be aware of:

Drug Interactions:

• Amiodarone: Combining alclometasone with amiodarone may decrease the metabolism of alclometasone.

• Amphotericin B: Alclometasone may enhance the hypokalemic (low potassium) effects of amphotericin B.

• Anthrax Immune Globulin, Human: Using alclometasone with this immune globulin can increase the risk or severity of adverse effects.

• Apalutamide: This combination may reduce the serum concentration of alclometasone.

• Aprepitant: Co-administration can increase the serum concentration of alclometasone.

• Atazanavir: Combining these drugs may decrease the metabolism of alclometasone.

• Cyclosporine: This combination may decrease the metabolism of alclometasone.

• Darunavir: Using alclometasone with darunavir can decrease the metabolism of alclometasone.

• Delavirdine: Combining these medications may decrease the metabolism of alclometasone.

• Diclofenac: Co-administration can increase the risk or severity of adverse effects.

• Mifepristone: Using alclometasone with mifepristone may decrease the therapeutic efficacy of alclometasone.

Disease Interactions:

• Diabetes: Topical corticosteroids like alclometasone can elevate blood glucose levels, potentially complicating diabetes management.

• Infections: Alclometasone may suppress the immune response, potentially worsening existing infections or increasing susceptibility to new infections.

• Ocular Toxicities: Prolonged use near the eyes can lead to increased intraocular pressure, glaucoma, or cataracts.

• Hyperadrenocorticism: Excessive use can lead to systemic absorption, potentially causing symptoms of hyperadrenocorticism (Cushing's syndrome).

• Diaper Rash: Alclometasone should not be used to treat diaper rash due to the risk of increased absorption and potential side effects in infants.

It's essential to inform your healthcare provider about all medications you're currently taking, including over-the-counter drugs and supplements, to avoid potential interactions. Always consult with your doctor before starting or stopping any medication.