Benlysta

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Belimumab, marketed as Benlysta, is a monoclonal antibody used in combination with other medications to manage systemic lupus erythematosus (SLE) and lupus nephritis in both adults and children aged 5 years and older. This drug functions as a BLyS-specific inhibitor, which reduces the activity of B cells in the immune system by blocking a protein called BLyS. This action helps to lower inflammation and can alleviate some lupus symptoms. Benlysta can be administered either through a weekly self-injection under the skin (subcutaneous) or as a monthly intravenous infusion provided by a healthcare professional. Common side effects may include nausea, diarrhea, and fever. Always consult with a healthcare provider before starting any new treatment.
Our Benlysta coupons are free to use. You can print the coupon, email it to yourself, or receive the Benlysta coupon via text message. To get your free discount, show the pharmacist your Benlysta savings card which has the discounted coupon price. Use our filters below to edit the prescription box to match your needs. The Benlysta prices will update based on your prescription needs. Above our Benlysta coupons, you can change the location to see pharmacy prices in other areas. Our prescription discount card will update online with the specific pharmacy costs associated with your edits. Be sure to text, email, or print the Benlysta savings card code that you need after editing the prescription box and location field. Show the discount card to your pharmacist before paying.

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1ML of 200MG/ML, Benlysta (1 Pen)

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$1232.96

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$1266.42

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$1285.87

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$1301.83

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Benlysta savings card

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Rite Aid

$1232.96

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The average cost for 1 Pen of Benlysta at 1ML of 200MG/ML is $1258.67 with a free coupon. This is 28.01% off the average retail price of $4493.81
DosageQuantityPrice fromPer unit
1ML of 200MG/ML1 Pen$1258.67$1258.67

Benlysta Warnings

The safety information for Benlysta (belimumab) is crucial for ensuring the well-being of those prescribed this medication. Please review the following information and discuss any concerns with your healthcare provider.

  • Increased Infection Risk: Benlysta (belimumab) can compromise your immune system, increasing the likelihood of serious infections such as pneumonia, urinary tract infections (UTIs), and bronchitis. If you experience symptoms like fever, cough, difficulty breathing, or chills, contact your healthcare provider immediately. Your medical team should be informed of your medical history and current medications to evaluate the safety of Benlysta (belimumab) for you.

  • Allergic Reactions: There is a potential for severe allergic reactions, including anaphylaxis, especially when administered intravenously. Symptoms may include rash, hives, and difficulty breathing, and can occur within hours or even a week after infusion. If you experience these symptoms, seek medical assistance immediately.

  • Mood Changes: Some patients have reported depression and suicidal thoughts while taking Benlysta (belimumab). It's essential to monitor any changes in mood or behavior and inform your healthcare provider promptly. If symptoms are severe, discontinuation of the medication may be necessary.

  • Vaccine Precautions: Do not receive live vaccines within 30 days before or during treatment with Benlysta (belimumab), as the medication might interfere with the vaccine's efficacy. Ensure all vaccinations are current prior to starting treatment, and inform your healthcare provider or pharmacist that you are taking Benlysta (belimumab) before receiving any vaccines.

Please adhere strictly to these guidelines and maintain open communication with your healthcare provider to ensure safe and effective use of Benlysta (belimumab).

Benlysta Side Effects

When using this medication, some common side effects may occur, though they are generally mild. These include nausea, diarrhea, fever, common cold symptoms, bronchitis, difficulty sleeping, and reactions at the injection site such as pain, redness, or itching. Additionally, some individuals may experience pain in the arms or legs, depression, migraine, and sore throat. If these symptoms persist or worsen, it is advisable to consult your healthcare provider for guidance.

There are also other side effects that may occur, such as bladder infections or urinary tract infections, and symptoms resembling the stomach flu. While these are less common, it is important to monitor how you feel and report any concerns to a healthcare professional.

More serious side effects, although rare, require immediate medical attention. These include severe infections characterized by confusion, fever, difficulty breathing, weakness, and other symptoms like a burning sensation during urination. Additionally, a serious allergic reaction may present with difficulty breathing, hives, a fast heartbeat, and swelling of the face or tongue. Depression and thoughts of self-harm are also serious and should be addressed by seeking medical help promptly.

In rare cases, the medication may lower your immune response, increasing the risk of serious infections or even cancer, including skin cancer. If you notice new skin lesions, changes in moles, or symptoms like night sweats and unexplained weight loss, contact a healthcare provider immediately. Furthermore, there is a small risk of developing a rare brain infection known as progressive multifocal leukoencephalopathy (PML), which can cause symptoms such as clumsiness, confusion, or vision changes. If you experience these, seek urgent medical assistance.

Always be attentive to how your body responds to the medication and communicate any unexpected effects to your healthcare provider for advice and support.

Benlysta Interactions

Benlysta (belimumab) can interact with other medications that may suppress the immune system or increase the risk of infection. Notable interactions include medications like natalizumab, rituximab, and Tofacitinib. If you are prescribed Benlysta along with these medications, your doctor might adjust the dosage or frequency of one or both drugs. Always inform your healthcare provider about all medicines and supplements you are taking, including prescriptions, over-the-counter drugs, vitamins, and herbal products, to help manage potential interactions effectively.
Benlysta FAQs
What exactly does Benlysta do?

Benlysta is a medication used to treat systemic lupus erythematosus (SLE) in patients who are receiving other lupus treatments. It works by targeting and inhibiting a specific protein called B-lymphocyte stimulator (BLyS), which is involved in the survival of B cells. By reducing the activity of BLyS, Benlysta helps decrease the number of abnormal B cells, thereby reducing disease activity and symptoms associated with lupus.

Benlysta is not like chemotherapy. While both are used to treat certain medical conditions, they work in different ways. Benlysta is a biologic medication specifically used to treat systemic lupus erythematosus (SLE) by targeting and inhibiting a specific protein involved in the immune response. Chemotherapy, on the other hand, is a broader category of drugs that target rapidly dividing cells and is commonly used in cancer treatment.

Benlysta and Hydroxychloroquine are not the same. Benlysta (belimumab) is a biologic medication used to treat systemic lupus erythematosus (SLE) by targeting specific proteins in the immune system. Hydroxychloroquine, on the other hand, is an antimalarial drug that is also used to manage symptoms of lupus and rheumatoid arthritis by modulating the immune system. They have different mechanisms of action and are used in different contexts within lupus treatment.

Benlysta is not commonly associated with weight gain as a side effect. However, individual reactions to medications can vary. If there are concerns about weight changes while taking Benlysta, it is advisable to consult with a healthcare provider for personalized advice and evaluation.

Some medications used to treat lupus that may cause weight gain include corticosteroids, such as prednisone. These medications can lead to increased appetite and fluid retention, contributing to weight gain. It is important for patients to discuss any concerns about side effects with their healthcare provider, who can offer guidance on managing weight while on these medications.

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