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Individuals with certain health conditions or those taking specific medications should exercise caution or avoid taking calcium, magnesium, and zinc supplements. These include:1. Kidney Disease: People with kidney disease may have difficulty processing these minerals, leading to potential toxicity.2. Hypercalcemia: Those with high levels of calcium in the blood should avoid additional calcium intake.3. Medication Interactions: These supplements can interact with certain medications, such as antibiotics and diuretics, affecting their absorption or efficacy.4. Allergies: Individuals with known allergies to any of the supplement components should avoid them.It is important for individuals to consult with a healthcare provider before starting any new supplement regimen, especially if they have underlying health conditions or are taking other medications.

Yes, calcium and magnesium can interact with certain medications. Calcium can interfere with the absorption of some antibiotics, such as tetracyclines and fluoroquinolones, as well as bisphosphonates used for osteoporosis. Magnesium can also affect the absorption of these antibiotics and may interact with medications like certain diuretics and proton pump inhibitors. It is important for individuals to consult with their healthcare provider or pharmacist to manage these potential interactions effectively.