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Celecoxib, a type of nonsteroidal anti-inflammatory drug (NSAID), carries certain risks and precautions that you should be aware of before using it. Below are key safety considerations:

• Heart Risks: Celecoxib may increase the risk of heart attack or stroke, which can occur at any time during treatment, especially with prolonged use. This risk is higher for older adults and individuals with heart disease or risk factors such as smoking, family history, high blood pressure, or diabetes. Avoid using this drug right before or after undergoing coronary artery bypass graft (CABG) surgery.

• Gastrointestinal Risks: The medication can sometimes lead to serious, possibly fatal bleeding in the stomach or intestines, which might occur without any warning signs. Older adults have a heightened risk of this side effect.

• Emergency Symptoms: Discontinue use and seek immediate medical attention if you experience severe side effects, including persistent stomach or abdominal pain, black or tarry stools, vomit resembling coffee grounds, chest pain, shortness of breath, unusual sweating, confusion, weakness on one side of the body, speech difficulties, or sudden changes in vision.

• Consultation: It is important to discuss with your doctor or pharmacist the potential benefits and risks associated with taking celecoxib to ensure it is appropriate for your condition.

By understanding these risks and precautions, you can make informed decisions about your health and safety while using celecoxib.

When taking this medication, some individuals may experience mild side effects such as stomach upset, diarrhea, dizziness, gas, or swelling of the ankles and feet. These side effects are generally manageable, but if they persist or worsen, it's important to inform a healthcare professional. To reduce dizziness and lightheadedness, it's advisable to rise slowly from sitting or lying positions.

While many people do not experience severe side effects, it is crucial to be aware of them. The celecoxib in this medication may cause an increase in blood pressure, so regular monitoring is recommended. Seek medical attention promptly if you notice serious side effects like pain, swelling, or warmth in the groin or calf area, signs of kidney problems such as changes in urine output, difficulty swallowing, or symptoms of heart failure like unusual tiredness or sudden weight gain.

In rare instances, this medication may exacerbate chest pain or lead to a heart attack, especially in individuals with severe heart disease. Symptoms such as worsening chest pain, chest or jaw pain, shortness of breath, or unusual sweating warrant immediate medical help. Additionally, though rare, serious liver disease can occur, indicated by persistent nausea or vomiting, loss of appetite, abdominal pain, yellowing of the skin or eyes, or dark urine.

A very serious allergic reaction to this drug is also rare, but immediate medical attention is necessary if symptoms like fever, swollen lymph nodes, rash, itching, swelling of the face, tongue, or throat, severe dizziness, or trouble breathing occur. Always consult a healthcare provider if any unusual side effects arise.

This medication can interact with several other drugs, which may impact its effectiveness or increase the risk of side effects. Medications that may interact include Aliskiren, ACE inhibitors (like Captopril and Lisinopril), angiotensin II receptor blockers (such as Valsartan and Losartan), Cidofovir, Lithium, and diuretics like Furosemide. Additionally, taking this medication with other drugs that may cause bleeding can increase bleeding risk. These include antiplatelet drugs like Clopidogrel and blood thinners such as Dabigatran, Enoxaparin, and Warfarin.

Be sure to examine all your prescription and over-the-counter medicine labels, as many contain pain relievers or fever reducers such as Aspirin and NSAIDs (like Naproxen, Ibuprofen, and Ketorolac) that are similar to Celecoxib, which could raise the likelihood of side effects when taken together. However, if your doctor has advised you to take low-dose aspirin (81-162 milligrams daily) for heart attack or stroke prevention, you should continue unless otherwise directed by your doctor.

Some products might also elevate blood pressure, so inform your pharmacist about all the products you are using, especially cough-and-cold products, diet aids, or NSAIDs like ibuprofen and naproxen, to ensure safe use.