Divalproex ER Coupons & Discount Card - Compare Prices Near You

This medication, Divalproex (Depakote), has associated safety concerns and warnings that are important for both patients and healthcare providers to understand. Please read the following information carefully, and consult your healthcare provider with any questions or concerns:

• Liver Risks: Divalproex can lead to serious, potentially life-threatening liver issues, especially within the first six months of treatment. Those with a history of liver problems, children under 2 years, individuals on multiple anti-seizure medications, or those with severe seizure disorders are at increased risk. Regular lab tests are advised to monitor liver function during treatment.

• Pregnancy Concerns: This medication can cause severe birth defects and affect a child's mental development if taken during pregnancy. It is crucial to use reliable birth control and discuss alternative treatments with your doctor if you are pregnant or may become pregnant. Contact your doctor immediately if you become pregnant while on this medication.

• Pancreatitis Risk: Although rare, inflammation of the pancreas (pancreatitis) can occur at any point during treatment with divalproex. Symptoms such as abdominal pain, nausea, vomiting, or fever require immediate medical attention.

• Suicidal Thoughts: There is an increased risk of suicidal thoughts or behavior, particularly in those with a history of depression. Family and friends should be vigilant for any changes in mood or behavior and contact a healthcare provider if concerns arise.

• Blood Cell Counts: Divalproex may cause a reduction in platelet count, increasing bleeding risk. Monitoring through regular blood tests is recommended, and any signs of unusual bruising or bleeding should be reported to your healthcare provider.

• Ammonia Levels: This medication can cause elevated ammonia levels in the blood, especially when taken with topiramate, leading to symptoms like fatigue, confusion, or vomiting. Seek medical help immediately if these symptoms occur.

• Severe Allergic Reactions: Rare but serious skin reactions can occur, including rashes and organ failure. Immediate medical attention is necessary if severe skin symptoms or allergic reactions develop.

• Drug Interactions: Be aware that certain medications can affect how the body processes divalproex, impacting its efficacy and side effects. Discuss all medications you are taking with your healthcare provider.

• Contraindications: Avoid using divalproex if you have a history of liver problems, certain genetic disorders (e.g., Alpers-Huttenlocher Syndrome), or if you are treating migraines. Children under 2 years with certain genetic disorders should not use this medication. Those who are or could become pregnant should use contraception or consider alternative treatments.

For any signs of overdose or severe reactions, seek emergency medical assistance immediately. Always discuss any concerns or symptoms with your healthcare provider to ensure safe and effective use of divalproex (Depakote).

Common side effects:

• Nausea
• Dizziness
• Drowsiness
• Hair loss
• Blurred or double vision
• Changes in menstrual periods
• Ringing in the ears
• Shakiness
• Unsteadiness
• Weight changes
• Headaches
• Low energy
• Stomach pain
• Accidental injury

Serious side effects:

• Mood changes
• Depression
• Suicidal thoughts
• Encephalopathy
• Allergic reactions (fever, swollen lymph nodes, rash, severe dizziness, breathing difficulties)
• Chest pain
• Unusual bleeding
• Irregular heartbeat
• Swelling of the hands or feet
• Uncontrolled eye movements
• Loss of consciousness

Interactions with high risk of serious adverse effects and should be avoided:

• Imipenem
• Doripenem
• Ertapenem
• Meropenem
• Orlistat
• Vorinostat
• Warfarin
• Lamotrigine

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Nortriptyline
• Clomipramine
• Ethosuximide
• Carbamazepine
• Topiramate
• Mefloquine
• Zidovudine
• Rifampin