HomeDrug ClassesHuman Platelet-Derived Growth Factors

Human Platelet-Derived Growth Factors: Uses, Common Brands, and Safety Info

Human Platelet-Derived Growth Factors (hPDGF) are drugs derived from human platelets used for tissue regeneration and wound healing. They have various medical applications including treatment of chronic wounds and musculoskeletal injuries. Common brands include Regranex and Avastin. Safety precautions should be followed and any adverse reactions should be reported to a healthcare professional. [30 tokens]

Drug Class Description

Human Platelet-Derived Growth Factors


Human Platelet-Derived Growth Factors (hPDGF) belong to a class of drugs that are derived from human platelets and are primarily used for the promotion of tissue regeneration and wound healing. Platelets are small blood cells that play a crucial role in the clotting process. The growth factors contained within these platelets help stimulate cellular growth, angiogenesis (formation of new blood vessels), and tissue repair mechanisms. These growth factors have a variety of medical applications, including the treatment of chronic wounds, diabetic ulcers, burns, and musculoskeletal injuries. hPDGF can also be used in certain dental procedures to aid in socket preservation, bone grafting, and the acceleration of healing after oral surgery.

Common Brands

Several brands manufacture and market hPDGF-based products, including Regranex, Platelet-Derived Growth Factor-BB (PDGF-BB), and Avastin. It is important to note that these brand names may vary depending on the country and region. Medical professionals will determine the most suitable brand and delivery method based on the specific condition and patient factors.


The safety of using hPDGF drugs depends on various factors, such as the patient's medical history, allergies, and concurrent medications. Before initiating treatment, it is crucial to inform your healthcare provider about any existing medical conditions or ongoing treatments. Possible side effects associated with hPDGF drugs can include local discomfort at the application site, such as redness, swelling, or itching. In rare cases, systemic allergic reactions may occur. It is essential to follow the prescribed dosage and application instructions provided by the healthcare professional to minimize the risk of adverse effects. As with any medication, hPDGF drugs should only be used under the supervision and guidance of a qualified healthcare professional. If you experience any unexpected or severe reactions while using hPDGF drugs, it is important to seek medical attention promptly. Note: The information provided here is for informational purposes only and should not replace professional medical advice. Always consult a healthcare professional for personalized recommendations and guidance regarding your medical condition and treatment options. Sources: - [Source 1] - [Source 2]

List of Human Platelet-Derived Growth Factors