HomeDrug ClassesInsulin / GLP-1 Agonist Combinations

Insulin / GLP-1 Agonist Combinations: Uses, Common Brands, and Safety Info

Insulin/GLP-1 agonist combinations are medications used to control blood sugar in type 2 diabetes. Common brands include Soliqua and Xultophy. They are generally safe but may cause side effects like nausea and low blood sugar. Dosage should be tailored for each patient, and regular follow-up is important.


Insulin/GLP-1 agonist combinations are a class of medications that combine the effects of insulin and glucagon-like peptide-1 (GLP-1) agonists. This unique combination offers an effective treatment option for patients with type 2 diabetes who have difficulty achieving optimal blood sugar control with other medications.


These combinations are primarily used to manage blood sugar levels in adults with type 2 diabetes. They are typically prescribed when other oral medications or basal insulin alone have not adequately controlled blood sugar levels. The dual action of insulin/GLP-1 agonist combinations helps to lower blood sugar levels throughout the day, especially after meals. This class of medications can also support weight management by promoting satiety and reducing appetite.

Common Brands

Some commonly prescribed brands of insulin/GLP-1 agonist combinations include: - Soliqua (insulin glargine/lixisenatide) - Xultophy (insulin degludec/liraglutide) It's important to note that these are not the only available brands, and different countries may have different brand names for these medications.


Insulin/GLP-1 agonist combinations have proven to be generally safe and effective for adults with type 2 diabetes. However, as with any medication, there are possible side effects and precautions to consider. Common side effects may include nausea, vomiting, diarrhea, and hypoglycemia (low blood sugar). It's essential for healthcare providers to carefully tailor the dosage based on each individual's needs to minimize the risk of hypoglycemia. Patients should be educated on recognizing and managing symptoms of low blood sugar and should have regular follow-up appointments to assess their treatment response and adjust the medication if necessary. Additionally, insulin/GLP-1 agonist combinations may have other precautions and contraindications, depending on the specific brand. Patients should inform their healthcare provider about any existing medical conditions or medications they are taking to ensure safe and effective treatment. In conclusion, insulin/GLP-1 agonist combinations are beneficial for patients with type 2 diabetes who require additional blood sugar control beyond that offered by oral medications or basal insulin. These combinations offer the advantage of effectively lowering blood sugar levels while also aiding in weight management. As with any medication, it is crucial to discuss potential side effects, precautions, and dosage adjustments with a healthcare provider to ensure safe and optimal treatment outcomes.

List of Insulin / GLP-1 Agonist Combinations