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NSAID / Acetaminophen Combinations: Uses, Common Brands, and Safety Info

NSAID / Acetaminophen combinations are medications used for pain relief and inflammation. Common brands include Excedrin and Advil Dual Action. Precautions should be taken to avoid potential side effects, especially for individuals with stomach ulcers, liver disease, or who consume alcohol. Consulting a healthcare professional is recommended.

NSAID / Acetaminophen Combinations


NSAID / Acetaminophen combinations are a class of medications that contain both a nonsteroidal anti-inflammatory drug (NSAID) and acetaminophen. These combinations are primarily used to relieve pain and reduce inflammation in conditions such as arthritis, headaches, dental pain, menstrual cramps, and minor injuries. By combining the properties of both medications, these combinations offer a more comprehensive approach to pain management.

Common Brands

Several common brands of NSAID / Acetaminophen combinations are available in the market. Some well-known brands include Excedrin, Midol, and Advil Dual Action. These brands offer various formulations designed to target specific types of pain, providing consumers with options that cater to their individual needs.


When used appropriately, NSAID / Acetaminophen combinations can be effective and safe. However, it is important to take certain precautions to minimize the risk of potential side effects. It is crucial to read and follow the instructions on the packaging or as advised by a healthcare professional. It's important to note that NSAIDs have a risk of causing stomach ulcers, bleeding, and other gastrointestinal complications, especially when used for an extended period or in high doses. Therefore, individuals with a history of stomach ulcers or gastrointestinal issues should consult their doctor before using NSAID / Acetaminophen combinations. Additionally, individuals with liver disease or those who regularly consume alcohol should exercise caution when using these combinations, as high doses of acetaminophen can cause liver damage. Always adhere to the recommended dosage and avoid taking multiple medications containing acetaminophen simultaneously to prevent accidental overdose. It is advisable to consult a healthcare professional before starting any new medication, especially if you have pre-existing medical conditions, take other medications, or are pregnant or breastfeeding. They can provide personalized advice, assess potential drug interactions, and ensure that the NSAID / Acetaminophen combination is appropriate for your specific situation. In summary, NSAID / Acetaminophen combinations are commonly used to relieve pain and reduce inflammation. While they can be effective, it is essential to follow the recommended dosage and take necessary precautions to ensure safety. Consulting a healthcare professional is always advisable to determine if these combinations are suitable for your needs.

List of NSAID / Acetaminophen Combinations