HomeDrug ClassesNSAID / Histamine-2 Antagonist Combinations

NSAID / Histamine-2 Antagonist Combinations: Uses, Common Brands, and Safety Info

NSAID/Histamine-2 Antagonist Combinations are medications used to treat conditions like heartburn and stomach ulcers. By combining NSAIDs and histamine-2 antagonists, they reduce inflammation and stomach acid production. Common brands include Brand 1, Brand 2, and Brand 3. Safety considerations include following guidance from healthcare professionals, disclosing medical history and medications, and being aware of potential side effects.


NSAID/Histamine-2 Antagonist Combinations are a class of medications that combine nonsteroidal anti-inflammatory drugs (NSAIDs) with histamine-2 antagonists. These combinations are used to provide relief from symptoms associated with conditions such as heartburn, gastroesophageal reflux disease (GERD), and stomach ulcers. By combining these two types of medications, NSAID/Histamine-2 Antagonist Combinations help to reduce inflammation and decrease the production of stomach acid.


NSAID/Histamine-2 Antagonist Combinations are primarily used to treat symptoms related to stomach acid and inflammation in the gastrointestinal tract. The NSAID component of these combinations helps reduce pain, inflammation, and fever, while the histamine-2 antagonist component helps reduce the production of stomach acid.

Some common conditions where these combinations are used include:

  • Heartburn

  • Gastroesophageal reflux disease (GERD)

  • Stomach ulcers

These combinations may also be used to facilitate the healing of existing ulcers and prevent the formation of new ones in certain individuals who are at an increased risk.

Common Brands

There are several brands available that offer NSAID/Histamine-2 Antagonist Combinations. It's important to note that specific brand names may vary depending on the country and region. Some widely recognized brands include:

These brands may contain different combinations of NSAIDs and histamine-2 antagonists, so it's crucial to consult a healthcare professional to determine which brand and combination is most suitable for individual needs.


While NSAID/Histamine-2 Antagonist Combinations have proven to be effective in relieving symptoms associated with stomach acid and inflammation, it's important to consider their safety profile. Like any medication, there are certain precautions and potential side effects to be aware of.

Some general safety considerations include:

  • These combinations should be taken under the guidance and supervision of a healthcare professional.

  • Prior medical conditions, allergies, and current medications should be disclosed to the healthcare provider to ensure the safe use of these combinations.

  • It is essential to follow the recommended dosage and schedule provided by the healthcare professional or indicated in the product packaging.

  • Common side effects may include upset stomach, drowsiness, dizziness, and headache. If any of these side effects persist or worsen, medical attention should be sought.

  • Individuals with certain conditions, such as asthma, kidney disease, or a history of gastrointestinal bleeding, may require cautious use or alternative treatment options.

It's important to note that this is not an exhaustive list of safety considerations, and there may be additional precautions specific to each brand and combination within the NSAID/Histamine-2 Antagonist class. Always consult a healthcare professional for personalized advice and guidance based on individual circumstances.

List of NSAID / Histamine-2 Antagonist Combinations