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Polypeptide Antibiotics: Uses, Common Brands, and Safety Info

Polypeptide antibiotics are effective in treating resistant bacterial infections, with common brands like Bacitracin and Colistin. Safety precautions should be taken, as they may cause skin irritation, kidney damage, and hearing loss. It is important to complete the full course of treatment to prevent antibiotic resistance.

Polypeptide Antibiotics

Polypeptide antibiotics are a class of drugs that are derived from natural sources such as bacteria or fungi. These antibiotics are composed of chains of amino acids and are generally used to treat a wide range of bacterial infections. They work by inhibiting the growth and reproduction of bacteria, ultimately leading to their destruction.


Polypeptide antibiotics are commonly used to treat infections caused by gram-positive bacteria. They are particularly effective against bacteria that are resistant to other types of antibiotics. These drugs are often used to treat skin and soft tissue infections, such as impetigo and cellulitis, as well as more serious infections such as pneumonia and sepsis.

Common Brands

Some common brands of polypeptide antibiotics include Bacitracin, Colistin, Polymyxin B, and Vancomycin. These drugs may be available in various formulations, including ointments, creams, and intravenous solutions. It is important to note that the availability of specific brands may vary depending on the country and region.


Polypeptide antibiotics are generally safe and well-tolerated when used as directed by a healthcare professional. However, like any medication, they can have potential side effects. Common side effects may include skin irritation, rash, or allergic reactions. If you experience any severe or persistent side effects, it is important to consult your healthcare provider. It is important to note that some polypeptide antibiotics, such as Colistin and Vancomycin, may have a higher risk of causing kidney damage or hearing loss, especially when used at high doses or for prolonged periods. Therefore, close monitoring of kidney function and hearing may be necessary during treatment with these antibiotics. As with any antibiotics, it is crucial to take the full course of treatment as prescribed by your healthcare provider, even if your symptoms improve before the medication is completed. This helps to ensure the complete eradication of the infection and prevent the development of antibiotic resistance. In conclusion, polypeptide antibiotics are an important class of drugs used to treat bacterial infections that are resistant to other types of antibiotics. They are effective against a range of infections and are generally safe when used as directed. However, it is important to be aware of the specific precautions and potential side effects associated with each individual drug within this class. Always consult with your healthcare provider for personalized advice and guidance regarding the use of polypeptide antibiotics.

List of Polypeptide Antibiotics