HomeDrug ClassesSGLT2 Inhibitor / Gliptin Combinations

SGLT2 Inhibitor / Gliptin Combinations: Uses, Common Brands, and Safety Info

SGLT2 inhibitor / gliptin combinations are drug classes used to treat type 2 diabetes by targeting different mechanisms to control blood sugar levels. They are used when other antidiabetic drugs have not been effective. Common brands include Brand A, Brand B, and Brand C. These combinations are generally safe but may cause side effects such as nausea, diarrhea, and urinary tract infections. Regular monitoring and lifestyle modifications are important for managing diabetes.

SGLT2 Inhibitor / Gliptin Combinations

SGLT2 inhibitor / gliptin combinations are a class of medications used in the treatment of type 2 diabetes mellitus. This drug class combines two different types of medications: SGLT2 inhibitors and gliptins (DPP-4 inhibitors). These combinations are specifically formulated to provide an enhanced therapeutic effect in controlling blood sugar levels in patients with diabetes.


SGLT2 inhibitor / gliptin combinations are prescribed to individuals with type 2 diabetes who have not adequately responded to other antidiabetic drugs, such as metformin or sulfonylureas. These combinations work by targeting different mechanisms in the body to help regulate blood glucose levels.

SGLT2 inhibitors work by inhibiting the reabsorption of glucose by the kidneys, resulting in increased glucose excretion through urine. Gliptins, on the other hand, work by inhibiting the enzyme responsible for degrading incretin hormones, which in turn increase insulin production and decrease glucagon release.

The combination of these two medications allows for better blood sugar control by acting on multiple pathways, leading to improved glycemic control and potentially reducing the risk of diabetic complications.

Common Brands

There are several brands available in the market that offer SGLT2 inhibitor / gliptin combination medications. These include:

  • Brand A

  • Brand B

  • Brand C

It is important to note that the availability of specific brands may vary depending on the region and country.


While SGLT2 inhibitor / gliptin combinations are generally considered safe and well-tolerated, it is crucial to follow the prescribed dosage and recommendations provided by your healthcare provider. Some common side effects that may occur include:

  • Nausea

  • Diarrhea

  • Urinary tract infections

  • Genital yeast infections

  • Hypoglycemia (low blood sugar) when used in combination with other antidiabetic medications

It is important to discuss any potential drug interactions or contraindications with your healthcare provider before starting SGLT2 inhibitor / gliptin combinations. Additionally, individuals with a history of kidney problems or urinary tract infections should exercise caution while using these medications.

Your healthcare provider will monitor your blood sugar levels periodically to ensure the medication is effective and adjust the dosage as needed. Regular check-ups and following a healthy lifestyle, including a balanced diet and regular exercise, are crucial components of managing diabetes.

In conclusion, SGLT2 inhibitor / gliptin combinations are a drug class used for the treatment of type 2 diabetes. These combinations provide an enhanced therapeutic effect by targeting different mechanisms to control blood sugar levels effectively. It is important to discuss with your healthcare provider regarding specific brands, safety considerations, and any potential side effects or interactions.

List of SGLT2 Inhibitor / Gliptin Combinations