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When considering treatment with Ebglyss, it's important to be aware of certain safety considerations:

• Allergic Reactions: Some individuals may experience serious allergic reactions to Ebglyss, such as swelling (angioedema) and hives (urticaria). If you notice symptoms like difficulty breathing, swelling of the face or throat, or a severe rash, discontinue use and seek immediate medical attention.

• Eye Health: Ebglyss has been associated with eye conditions, including conjunctivitis (pink eye) and keratitis (inflammation of the cornea). These conditions were more common in patients treated with Ebglyss compared to those who received a placebo. Most cases were mild or moderate and resolved during treatment. However, if you experience new or worsening eye symptoms, such as redness, pain, or vision changes, inform your healthcare provider promptly.

• Parasitic Infections: The effect of Ebglyss on parasitic (helminth) infections is not well understood. It's recommended to treat any existing parasitic infections before starting Ebglyss. If you develop a parasitic infection during treatment and it doesn't respond to standard therapy, discontinuing Ebglyss may be necessary until the infection is resolved.

• Vaccinations: Ebglyss may affect your immune response to live vaccines, potentially increasing the risk of infection. Ensure all age-appropriate vaccinations are completed before beginning treatment. Avoid receiving live vaccines immediately before or during Ebglyss therapy.

• Pregnancy and Breastfeeding: The safety of Ebglyss during pregnancy and breastfeeding is not established. If you're pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits with your healthcare provider before starting treatment.

Always consult your healthcare provider to determine if Ebglyss is appropriate for you, considering your medical history and current health status.

When considering Ebglyss (lebrikizumab-lbkz) for the treatment of moderate-to-severe atopic dermatitis, it's important to be aware of potential interactions with other medications and vaccines.

Live Vaccines: Ebglyss may affect your immune system's response to live vaccines, potentially increasing the risk of infection. Therefore, it's recommended to complete all age-appropriate vaccinations before starting Ebglyss. Avoid receiving live vaccines immediately before or during treatment with Ebglyss. Examples of live vaccines include the measles, mumps, and rubella (MMR) vaccine, the chickenpox (varicella) vaccine, and the live influenza (flu) vaccine.

Other Medications: Currently, there are no well-documented interactions between Ebglyss and other medications. However, it's essential to inform your healthcare provider about all prescription and over-the-counter medicines, vitamins, and herbal supplements you are taking. This ensures they can monitor for any potential interactions and manage your treatment plan effectively.

Parasitic Infections: Ebglyss may increase the risk of certain parasitic (helminth) infections. If you have a known parasitic infection, it should be treated before initiating Ebglyss. If you become infected while on Ebglyss and do not respond to anti-parasitic treatment, discontinuation of Ebglyss may be necessary until the infection resolves.

Always consult your healthcare provider for personalized advice regarding potential interactions and to ensure Ebglyss is safe and appropriate for your specific health needs.