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Flovent (fluticasone) is a medication used to manage certain respiratory conditions. It is important to be aware of the potential risks and necessary precautions associated with its use. Please read the following safety information carefully and consult your healthcare provider if you have any questions or concerns.

• Fungal Infections in the Mouth: Using Flovent (fluticasone) can lead to a fungal infection known as thrush in the mouth and throat. To minimize this risk, rinse your mouth with water and spit after each use. If you experience symptoms such as white patches, a cotton-like feeling, pain when eating or swallowing, or loss of taste, contact your healthcare provider. Antifungal treatment may be needed.

• Airway Narrowing (Bronchospasm): This medication can cause bronchospasm, a condition that results in difficulty breathing, wheezing, coughing, and chest discomfort. If you experience shortness of breath after using Flovent (fluticasone), use a rescue inhaler and seek medical help immediately.

• Severe Allergic Reactions: Some individuals may experience severe allergic reactions, including facial swelling, shock, and anaphylaxis. If you notice symptoms such as hives, rash, red skin, swelling of the lips or tongue, or difficulty breathing, seek emergency medical attention.

• Altered Stress Hormone Levels: Prolonged or excessive use of Flovent (fluticasone) can lead to changes in cortisol levels, which may result in symptoms like weight gain, facial puffiness, and muscle weakness, or symptoms of low cortisol such as fatigue, loss of appetite, nausea, and vomiting. Use the medication as prescribed and avoid exceeding the recommended dose.

• Delayed Growth in Children: There is a possibility of growth delay in children using Flovent (fluticasone). Discuss any concerns with your child's healthcare provider to determine if this medication is suitable for them. Children should use the lowest effective dose for the shortest duration possible.

• Eye and Vision Problems: Long-term use of Flovent (fluticasone) has been associated with increased eye pressure, glaucoma, and cataracts. If you have a history of these conditions or notice any changes in vision, consult your eye care professional.

Contraindications:

• Flovent (fluticasone) should not be used for treating a sudden asthma attack. Consult your healthcare provider for appropriate treatment options in such cases.

For any concerns or unusual symptoms while using Flovent (fluticasone), contact your healthcare provider promptly for guidance.

Common side effects:

• Throat irritation
• Headache
• Voice hoarseness
• Difficulty speaking

Less common but important to monitor:

• Upper respiratory tract infections
• Sinus infections
• Cough
• Oral thrush
• Nausea
• Vomiting
• Stomach upset
• Fever
• Bronchitis
• Muscle pain

Serious side effects:

• Severe allergic reaction (rash, hives, swelling of the face, tongue, or throat, difficulty breathing)
• Sudden severe wheezing or trouble breathing
• Changes to stress hormone levels (weight gain, puffiness of the face, muscle weakness, easy bruising, mood changes)

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• desmopressin
• ketoconazole
• lopinavir
• ritonavir