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Pramoxine is used to temporarily relieve itching and pain caused by minor skin irritation such as minor burns/cuts/scrapes, sunburn, eczema, insect bites, cold sores, or rashes from poison ivy, poison oak, or poison sumac. Some products containing pramoxine are also used to temporarily relieve the itching and discomfort from hemorrhoids and certain other problems of the genital/anal area (such as anal fissures, itching around the vagina/rectum). Pramoxine belongs to a class of drugs known as local anesthetics. It works by numbing the skin to block the feelings of pain and itching. This product may also contain other ingredients including skin protectants (such as calamine, zinc acetate, zinc oxide). Read the product package for more information. Do not use pramoxine for skin irritation in children younger than 2 years or use pramoxine for hemorrhoids or other genital/anal conditions in children younger than 12 years unless directed by the doctor. If you are self-treating with this medication, it is important to read the package instructions carefully before you start using this product to be sure it is right for you.