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The following safety information outlines important risks and considerations associated with the use of ketamine (Ketalar). Please review this information carefully and consult your healthcare provider with any concerns or questions.

• Vital Sign Changes: Ketamine can cause fluctuations in blood pressure and heart rate, as well as potential irregular heartbeats. Medical professionals will monitor your vital signs and heart function during treatment.

• Post-Procedure Reactions: After waking from anesthesia, some individuals may experience confusion, hallucinations, or a dreamy state. Such effects can lead to excitement or irrational behavior. These reactions may last for several hours, depending on dosage and administration method. To reduce these effects, additional medications may be given, or efforts will be made to ensure a quiet recovery environment.

• Respiratory Issues: Administering ketamine too rapidly or in excessive amounts can lead to breathing difficulties. Healthcare providers will oversee your breathing and oxygen levels and adjust dosages as necessary to prevent such issues.

• Risks for Newborns and Children: The safety of ketamine for pregnant women, unborn children, and individuals under 16 is uncertain. It is crucial to discuss the potential risks and benefits with your healthcare provider, especially if anesthesia is required for necessary procedures.

• Liver Health: Repeated use of ketamine may increase the risk of liver problems. Liver function will be monitored in patients receiving frequent or repeated doses.

• Drug Interactions: Ketamine can interact with various medications. Inform your healthcare provider about all the medications you are currently taking. Specific drugs, such as theophylline or aminophylline, may increase the risk of seizures when combined with ketamine. Additionally, using ketamine with substances that depress the central nervous system, such as opioids, benzodiazepines, or alcohol, can lead to severe sedation, respiratory issues, coma, or death. Doses may be adjusted, and monitoring increased to ensure patient safety.

Consult with your healthcare provider for personalized advice and to address any specific concerns you may have about using ketamine (Ketalar).