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It is crucial to be aware of important safety information regarding the use of levocarnitine (Carnitor). Below are key points to consider to ensure safe and effective use of this medication:

• Allergic Reactions: There is a risk of severe allergic reactions, including potentially life-threatening anaphylaxis, associated with levocarnitine (Carnitor). Signs of an allergic reaction include hives, rash, swelling of the lips or tongue, or difficulty breathing. In cases of anaphylaxis, seek emergency medical help immediately by calling 911. For other allergic symptoms, contact your healthcare provider promptly.

• Seizure Risk: Levocarnitine (Carnitor) can increase the likelihood of seizures, particularly in individuals with a history of seizures or epilepsy. It is important to discuss all your current medications with your healthcare provider and pharmacist to identify any that may also increase seizure risk. If a seizure occurs while taking levocarnitine (Carnitor), report it to your healthcare provider right away.

Please consult your healthcare provider for personalized advice and to address any concerns you may have regarding the use of levocarnitine (Carnitor).

Common side effects:

• nausea
• vomiting
• stomach cramps
• diarrhea
• headache
• muscle pain
• muscle weakness
• distinct body odor
• tingling skin

Less common but important to monitor:

• swelling of the hands
• swelling of the lower legs
• swelling of the feet

Serious side effects:

• seizures
• severe allergic reactions
• rash
• itching
• hives
• swelling of the face
• swelling of the tongue
• swelling of the throat
• severe dizziness
• difficulty breathing

L-carnitine, a naturally occurring amino acid derivative, plays a vital role in energy production by transporting fatty acids into the mitochondria. While it is generally safe for most individuals, it's important to be aware of potential interactions with certain medications:

• Anticoagulants (Blood Thinners): L-carnitine may enhance the effects of anticoagulant medications such as Warfarin and acenocoumarol. This can increase the risk of bleeding and bruising. Individuals taking these medications should have their blood clotting parameters monitored regularly, and dosage adjustments may be necessary.

• Thyroid Hormones: L-carnitine can interfere with thyroid hormone activity, potentially reducing the effectiveness of thyroid medications. Those on thyroid hormone replacement therapy should consult their healthcare provider before starting L-carnitine supplements.

• Anticonvulsants: Certain anticonvulsant drugs, including Valproic Acid, Phenobarbital, Phenytoin, and Carbamazepine, may lower L-carnitine levels in the body. Supplementing with L-carnitine might be beneficial in such cases, but it's essential to do so under medical supervision to avoid adverse effects.

• Antibiotics: Some antibiotics, particularly those conjugated with pivalate like pivampicillin, can lead to increased excretion of L-carnitine, potentially resulting in deficiency. Long-term use of these antibiotics should be monitored to prevent depletion of L-carnitine levels.

• Cholesterol-Lowering Medications (Statins): There is evidence suggesting that L-carnitine might reduce the effectiveness of statins, medications commonly prescribed to lower cholesterol levels. Individuals on statin therapy should consult their healthcare provider before combining it with L-carnitine supplements.

• Antidepressants (SSRIs): Combining L-carnitine with selective serotonin reuptake inhibitors (SSRIs), a class of antidepressants, may increase the risk of serotonin syndrome, a potentially serious condition. It's crucial to discuss with a healthcare provider before using L-carnitine alongside SSRIs.

Given these potential interactions, it's advisable to consult with a healthcare professional before adding L-carnitine supplements to your regimen, especially if you are taking any of the medications mentioned above.