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When using the Monistat 3 Combination Pack, it's important to be aware of certain precautions to ensure safe and effective treatment. This product is intended for vaginal use only. If you've never had a vaginal yeast infection diagnosed by a doctor, consult a healthcare professional before using this medication.

Before starting treatment, seek medical advice if you experience any of the following:

• Vaginal itching and discomfort for the first time.

• Lower abdominal, back, or shoulder pain, fever, chills, nausea, vomiting, or foul-smelling vaginal discharge, as these may indicate a more serious condition.

• Frequent vaginal yeast infections (such as once a month or three in six months), which could suggest pregnancy or an underlying medical issue like diabetes or a weakened immune system.

• Exposure to the human immunodeficiency virus (HIV) that causes AIDS.

While using this product, avoid tampons, douches, spermicides, or other vaginal products, as they may interfere with treatment effectiveness. Additionally, condoms and diaphragms may be damaged, potentially failing to prevent pregnancy or sexually transmitted diseases. Refrain from vaginal intercourse during treatment.

If symptoms do not improve within three days, persist beyond seven days, or if you develop a rash, hives, abdominal pain, fever, chills, nausea, vomiting, or foul-smelling vaginal discharge, discontinue use and consult a doctor.

If you are pregnant or breastfeeding, seek advice from a healthcare professional before using this product.

Keep the product out of reach of children. In case of accidental ingestion, get medical help or contact a Poison Control Center immediately.

When using the Monistat 3 Combination Pack, it's important to be aware of potential interactions with other medications. The active ingredient, Miconazole, can affect how certain drugs work in your body.

One notable interaction is with Warfarin, a medication used to prevent blood clots. Miconazole may enhance the effects of warfarin, increasing the risk of bleeding or bruising. If you're taking warfarin, consult your doctor or pharmacist before using Monistat 3.

Additionally, miconazole can interact with other medications metabolized by specific liver enzymes, potentially altering their effectiveness. This includes drugs like Pimozide, certain statins (such as Simvastatin and Lovastatin), and some medications used to treat migraines, like Dihydroergotamine. Using Monistat 3 alongside these medications may lead to serious side effects. Therefore, it's crucial to inform your healthcare provider about all the medications you're currently taking, including over-the-counter drugs and supplements, before starting treatment with Monistat 3.

Furthermore, miconazole may weaken latex products like condoms and diaphragms, reducing their effectiveness in preventing pregnancy and sexually transmitted infections. It's advisable to avoid using these products during treatment and for a short period afterward.

Always read the product's instructions carefully and consult with a healthcare professional if you have any concerns about potential drug interactions.