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When using this medication, some mild side effects such as itching, redness, burning, or stinging at the application site might occur. If the redness persists beyond four days, discontinue use and consult your healthcare provider. Other side effects can include nausea, dizziness, flushing, heartburn, or headaches. It's common to experience nicotine withdrawal symptoms like dizziness, anxiety, depression, or trouble sleeping when you stop smoking. If these symptoms or any side effects worsen, it's important to speak with your healthcare provider promptly.

Be aware that serious side effects may occur, particularly if smoking is continued while using this medication. These include mood changes such as irritability or vivid dreams, numbness or tingling in the extremities, and swelling of the hands, ankles, or feet. In the event of very serious side effects like chest pain, confusion, severe headache, rapid or irregular heartbeat, difficulty speaking, or weakness on one side of the body, discontinue use and seek immediate medical attention.

Although a severe allergic reaction to this medication is rare, it's crucial to get emergency medical help if you experience symptoms such as a rash, itching or swelling (particularly of the face, tongue, or throat), severe dizziness, or difficulty breathing. This summary does not include all possible side effects, so if you notice any other unusual symptoms, contact your healthcare provider for guidance.