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When using this medication, you may experience mild side effects such as itching, redness, burning, or stinging at the application site. These are common and usually not a cause for concern unless the redness persists beyond four days, in which case you should consult a healthcare professional. Other possible mild side effects include nausea, dizziness, flushing, heartburn, or headache. These should be manageable but if they persist or worsen, it's important to seek advice from a healthcare provider.

Nicotine withdrawal symptoms may also occur, especially when you stop smoking. These can include dizziness, anxiety, depression, or trouble sleeping. While these are uncomfortable, they are generally not serious.

Be aware of serious side effects, which necessitate discontinuing the medication and consulting a healthcare provider immediately. These include mental or mood changes like irritability, trouble sleeping, vivid dreams, numbness or tingling in hands or feet, and swelling of hands, ankles, or feet. More severe reactions require urgent medical attention, such as chest pain, confusion, severe headache, irregular heartbeat, trouble speaking, or weakness on one side of the body.

Although rare, a serious allergic reaction could occur, characterized by rash, itching, swelling (particularly of the face, tongue, or throat), severe dizziness, or breathing difficulties. If these occur, seek medical help immediately. Always contact your healthcare provider if you notice any other effects not mentioned here.