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Nifedipine is primarily used to treat high blood pressure (hypertension) and angina (chest pain). It works by relaxing the blood vessels, which allows blood to flow more easily and reduces the heart's workload.

Nifedipine is still used in clinical practice, but its use has evolved over time. It is primarily used for the management of hypertension and angina. However, immediate-release formulations of nifedipine are less commonly used due to concerns about potential side effects, such as rapid drops in blood pressure and reflex tachycardia. Extended-release formulations are preferred as they provide more stable blood pressure control and have a better safety profile. As with any medication, the choice to use nifedipine depends on the individual patient's condition and the healthcare provider's judgment.

The most common side effect of nifedipine is peripheral edema, which is swelling of the lower limbs.

When taking nifedipine, one should avoid consuming grapefruit or grapefruit juice, as it can increase the levels of the medication in the bloodstream, potentially leading to increased side effects. Additionally, alcohol should be avoided or limited, as it can enhance the blood pressure-lowering effects of nifedipine, leading to dizziness or fainting. It's also important to avoid activities that require alertness, such as driving, until you know how the medication affects you. Always consult with a healthcare provider for personalized advice.

Nifedipine is generally considered safe when prescribed by a healthcare provider and taken as directed. However, like all medications, it can have potential side effects and interactions. It is important for patients to discuss their medical history and any other medications they are taking with their healthcare provider to ensure nifedipine is appropriate for their condition. Regular monitoring and follow-up with the healthcare provider are recommended to manage any potential risks.