Nylidrin

Drug Details

Nylidrin, also known as buphenine, is a medication that was used to treat peripheral vascular disorders and certain mental conditions in adults. It works by stimulating beta-adrenergic receptors, leading to the dilation of blood vessels, increased heart rate, and improved blood flow to various organs, including the brain. This enhanced circulation was believed to benefit conditions such as Raynaud’s phenomenon, arteriosclerosis, and diabetic vascular issues. However, the U.S. Food and Drug Administration (FDA) withdrew nylidrin from the U.S. market due to a lack of substantial evidence supporting its effectiveness in improving cerebral blood flow. Common side effects associated with nylidrin included nausea, vomiting, trembling, dizziness, palpitations, and a drop in blood pressure upon standing. Additionally, research has indicated that nylidrin may have antiviral properties by targeting the hemagglutinin 2 protein of the influenza A virus, thereby inhibiting viral entry into host cells.