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This medication is primarily used to treat specific liver conditions, but it poses significant risks, including the potential for severe or even fatal deterioration of liver function. Here are key safety warnings and precautions to consider:

• Liver Function Monitoring: Before you begin treatment, your healthcare provider should conduct laboratory tests to assess your liver function. This medication is contraindicated for individuals with specific liver diseases. Continuous monitoring through lab tests is necessary during treatment to detect any signs of worsening liver function. Discuss the potential risks and benefits thoroughly with your doctor.

• Worsening Liver Conditions: The use of this medication, particularly Ocaliva (obeticholic acid), can lead to serious liver issues, including liver failure. Individuals with primary biliary cholangitis and liver cirrhosis have experienced worsening liver conditions, necessitating liver transplant in some cases.

• Itchiness: There is a risk of severe itching that can disrupt daily life and sleep. Should you experience intense itching, consult your healthcare provider. They may suggest alternative treatments or adjust your medication dosage.

• Cholesterol Levels: This medication can reduce the levels of "good" cholesterol (HDL) in your body. Regular lab tests are essential to ensure your cholesterol levels remain within a safe range. If HDL levels drop significantly and there is no liver improvement after one year, discontinuation of the medication might be necessary.

• Contraindications: This medication should not be used if you have a history of worsening liver function, specific severe liver scarring (cirrhosis), or a complete bile duct blockage. Consult your healthcare provider if any of these conditions apply to you before starting treatment.

In the event of an overdose or adverse reaction, it is critical to seek immediate medical attention. Always communicate openly with your healthcare provider about any symptoms or concerns during your treatment.

When taking this medication, some individuals may experience common side effects that are typically mild. These include tiredness, throat or stomach pain, itching, rash, joint pain, dizziness, constipation, swelling in the arms or legs, and a feeling of the heart pounding. While these are generally not serious, it is important to inform your healthcare provider if they persist or worsen.

In rare instances, more severe side effects can occur, which require immediate medical attention. These include signs of worsening liver problems such as persistent nausea, vomiting, diarrhea, loss of appetite, abdominal pain, yellowing of the skin or eyes, dark urine, black stools, vomit resembling coffee grounds, a swollen abdomen, and unusual changes in urination. Additionally, mental changes such as dizziness, lightheadedness, fever, chills, or mood alterations should be monitored closely.

Serious allergic reactions, although rare, need urgent medical care if symptoms like rash, swelling, severe dizziness, or breathing difficulties appear. Some users have also reported changes in thyroid function and eczema. If you notice any side effects not listed, consult your healthcare provider promptly. Your health and safety are paramount, so ensure you seek medical advice as needed.