Pirfenidone Coupons & Discount Card – Guaranteed Prices from $323.66
generic Esbriet
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267MG, Pirfenidone (30 Capsules)
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Walgreens
$323.66
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Rite Aid
$877.79
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$323.66
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019876
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Pirfenidone dosage forms
| Dosage | Quantity | Price from | Per unit |
|---|---|---|---|
| 267MG | 30 Capsules | $323.66 | $10.79 |
Pirfenidone Warnings
Pirfenidone (Esbriet) comes with several important safety warnings that you should be aware of before starting treatment. It is crucial to discuss these with your healthcare provider to ensure safe use of the medication. Below, key warnings and precautions are outlined:
Liver Injury: Pirfenidone may cause liver damage, which can be serious or even life-threatening. Your healthcare provider will monitor your liver function by checking liver enzyme levels before starting treatment and regularly thereafter—monthly for the first six months, then every three months, or as needed. If you experience severe nausea, vomiting, pain in the right side of your abdomen, extreme tiredness, loss of appetite, or yellowing of the skin or eyes, seek medical attention immediately.
Sunlight Sensitivity: This medication can increase your sensitivity to sunlight and UV light, heightening the risk of sunburn even on cloudy days or during winter. To protect yourself, apply sunscreen with an SPF of 50 or higher and wear long-sleeved clothing when outdoors. Limiting sun exposure and avoiding tanning lamps are also recommended, particularly if you are taking other medications that heighten sun sensitivity.
Severe Skin Reactions: Although very rare, serious and potentially life-threatening skin reactions such as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), or drug reaction with eosinophilia and systemic symptoms (DRESS) may occur. If you notice skin changes such as rashes, blisters, redness, or peeling, or experience symptoms like fever and swollen lymph nodes, discontinue use and seek immediate medical care. If diagnosed with one of these conditions, you should cease using pirfenidone permanently.
Stomach-related Side Effects: Commonly, pirfenidone can cause stomach issues such as nausea, stomach pain, diarrhea, and indigestion, particularly in the first three months of treatment. These effects typically subside over time. However, consult your healthcare provider if they persist or worsen.
For your safety, always discuss any concerns or symptoms with your healthcare provider promptly.
Pirfenidone Side Effects
Common side effects:
- Nausea
- Rash
- Stomach discomfort
- Upper respiratory infections
- Diarrhea
- Tiredness
- Headache
- Reduced appetite
- Indigestion
- Dizziness
- Vomiting
Less common but important to monitor:
- Heartburn
- Sinus inflammation
- Difficulty sleeping
- Weight loss
- Joint pain
- General weakness
- Skin sensitivity
- Itchiness
- Changes in taste
- Non-heart-related chest pain
Serious side effects:
- Signs of liver damage (persistent nausea, vomiting, loss of appetite, stomach pain, yellowing of the skin or eyes, dark urine)
- Serious allergic reactions (fever, swollen lymph nodes, rash, blisters, mouth sores, itching, swelling, severe dizziness, trouble breathing)
Pirfenidone Interactions
Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:
- rifamycins (such as rifampin)
- drugs used to treat seizures (such as phenytoin)
- cigarette smoking
What are the most common side effects of pirfenidone?
The most common side effects of pirfenidone include nausea, fatigue, diarrhea, dyspepsia (indigestion), and rash. Other possible side effects can include headache, dizziness, and decreased appetite. It is important for patients to discuss any side effects they experience with their healthcare provider.
What is the life expectancy of someone on pirfenidone?
The life expectancy of someone taking pirfenidone can vary significantly depending on the underlying condition being treated, the stage of the disease, and individual patient factors. Pirfenidone is commonly used to treat idiopathic pulmonary fibrosis (IPF), a progressive lung disease. While pirfenidone can help slow the progression of IPF and improve quality of life, it does not cure the disease. Life expectancy in IPF patients can range widely, and it is best discussed with a healthcare provider who can consider the specific circumstances of the patient.
What is the drug pirfenidone used for?
Pirfenidone is used for the treatment of idiopathic pulmonary fibrosis (IPF), a condition characterized by progressive scarring of the lungs. It helps to slow down the decline in lung function associated with this disease.
What is the warning for pirfenidone?
Pirfenidone carries several warnings that patients should be aware of. It may cause liver problems, so liver function tests should be conducted before and during treatment. Patients should be monitored for signs of liver dysfunction, such as jaundice or dark urine. Pirfenidone can also cause photosensitivity reactions, so patients are advised to avoid or minimize sun exposure and use sunscreen. Additionally, it may cause gastrointestinal side effects, such as nausea and diarrhea. Patients should report any severe or persistent symptoms to their healthcare provider.
Does pirfenidone make you tired?
Yes, pirfenidone can cause fatigue as a side effect. It is important for patients to monitor how they feel and discuss any concerns with their healthcare provider, especially if the fatigue is affecting their daily activities.