
Propylthiouracil Coupons & Discount Card – Guaranteed Prices from $5.02
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50MG, Propylthiouracil (30 Tablets)
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CVS
$20.70
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Walgreens
$5.02
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$12.81
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$13.14
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$19.76
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Walgreens
$5.02
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019876
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Propylthiouracil dosage forms
Dosage | Quantity | Price from | Per unit |
---|---|---|---|
50MG | 30 Tablets | $5.02 | $0.17 |
Propylthiouracil Warnings
Propylthiouracil is a medication that comes with several important safety warnings and precautions. It is crucial to understand these potential risks and discuss them with your healthcare provider to ensure safe use of the drug. Here are the key points to consider:
Liver Damage: There is a rare but serious risk of liver injury associated with propylthiouracil, especially within the first six months of treatment. Regular blood tests are recommended to monitor liver health. Contact your healthcare provider immediately if you experience nausea or vomiting that persists, severe stomach or abdominal pain, dark urine, or yellowing of the eyes or skin. Individuals with a history of liver problems should be particularly cautious.
Risks During Pregnancy: Propylthiouracil should only be used during the first trimester of pregnancy if absolutely necessary due to its potential to cause severe liver damage in the mother. Pregnant individuals or those planning to become pregnant should consult their healthcare provider to determine if this medication is appropriate.
Immune System Suppression: On rare occasions, propylthiouracil can decrease white blood cell counts, leading to a weakened immune system. This may increase the risk of infections, particularly if you are also taking other medications that suppress the immune system. Seek medical advice promptly if you develop a fever or sore throat while on this medication.
Hypothyroidism Risk: Propylthiouracil can sometimes lower thyroid hormone levels excessively, resulting in hypothyroidism. Regular monitoring through blood tests is necessary to keep hormone levels within a normal range. If you are pregnant, it is crucial to maintain the correct dosage, as excessive amounts can affect fetal growth.
Blood Vessel Inflammation: Rarely, this medication may cause vasculitis, an inflammation of the blood vessels, which can impact various organs such as the kidneys, lungs, brain, and colon. Notify your healthcare provider immediately if you have difficulty urinating, experience lower back pain, abdominal swelling and pain, fever, or notice blood in your urine or stool. This risk is heightened for those with a history of kidney problems.
In case of a suspected overdose, seek emergency medical assistance immediately. Always follow your healthcare provider's instructions and inform them of any other medications you are taking to avoid potential interactions.
Propylthiouracil Side Effects
Common side effects:
- nausea
- vomiting
- stomach upset
- mild rash or itching
- headache
- tingling sensations
- joint or muscle pain
- dizziness
- loss or change in taste
- swelling
Less common but important to monitor:
- skin rash
- skin discoloration
- vertigo
- yellowing of the eyes
Serious side effects:
- signs of low blood cell counts (fever, chills, cough, muscle aches)
- symptoms of potential liver damage (stomach pain, clay-colored stools, yellowing of the skin or eyes)
- signs of bleeding
- severe skin reactions (blisters or peeling)
Propylthiouracil Interactions
Interactions with high risk of serious adverse effects and should be avoided:
- Macimorelin
- Pexidartinib
Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:
- Acenocoumarol
- Anisindione
- Dicumarol
- Phenindione
- Phenprocoumon
- Warfarin
What is the drug propylthiouracil used for?
Propylthiouracil is used to treat hyperthyroidism, which is an overactive thyroid gland. It works by decreasing the amount of thyroid hormone produced by the thyroid gland.
What to avoid when taking propylthiouracil?
When taking propylthiouracil, it is important to avoid the following:1. Iodine-rich foods and supplements: These can interfere with the effectiveness of the medication. Foods high in iodine include seaweed, fish, and iodized salt.2. Certain medications: Some medications may interact with propylthiouracil, such as anticoagulants, beta-blockers, and other thyroid medications. It is important to inform the healthcare provider of all medications being taken.3. Alcohol: It is advisable to limit alcohol consumption, as it can increase the risk of liver damage, a potential side effect of propylthiouracil.4. Pregnancy and breastfeeding: Women who are pregnant or breastfeeding should consult their healthcare provider, as propylthiouracil can affect the fetus or nursing infant.5. Infection exposure: Since propylthiouracil can lower white blood cell counts, it is important to avoid exposure to infections and report any signs of infection, such as fever or sore throat, to a healthcare provider immediately.Patients should follow their healthcare provider's instructions and discuss any concerns or questions they have about their treatment.
When is PTU preferred over methimazole?
Propylthiouracil (PTU) is preferred over methimazole in certain situations, such as during the first trimester of pregnancy due to the risk of teratogenic effects associated with methimazole. PTU is also preferred in cases of thyroid storm because it has the additional benefit of inhibiting peripheral conversion of T4 to T3. Additionally, PTU may be considered if a patient has experienced adverse reactions to methimazole.
What organs are affected by propylthiouracil?
Propylthiouracil primarily affects the thyroid gland as it is used to manage hyperthyroidism by inhibiting thyroid hormone synthesis. However, it can also impact other organs, particularly the liver, as it has been associated with hepatotoxicity. Additionally, it can affect the bone marrow, leading to conditions such as agranulocytosis, which is a significant reduction in white blood cells. Regular monitoring of liver function and blood cell counts is recommended during treatment.
Is methimazole or propylthiouracil better for thyroid storm?
In the management of thyroid storm, propylthiouracil (PTU) is generally preferred over methimazole. This is because PTU has the added benefit of inhibiting the peripheral conversion of T4 to T3, which is particularly useful in the acute setting of a thyroid storm. However, the choice of medication should be guided by the patient's specific clinical situation and any potential contraindications.