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This vaccine is used to help prevent a certain virus infection (rotavirus) in infants and young children. The infection can cause fever, vomiting, and diarrhea, which can lead to severe (rarely fatal) dehydration. Vaccination is the best way to protect against this infection. This vaccine contains live viruses that have been weakened. It works by increasing the body's natural defense (immunity) against the virus. Vaccines may not fully protect everyone who receives them.