Skyclarys

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Omaveloxolone, marketed as Skyclarys, is an approved medication for treating Friedreich's ataxia (FA), a rare genetic condition impacting nerves and muscles, primarily in individuals aged 16 and older. This disorder leads to nerve damage, resulting in loss of coordination and unsteady movements. Omaveloxolone is available in capsule form and is taken orally once daily. It functions as an activator of the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway, which is involved in reducing inflammation to prevent tissue and cell damage. While the exact mechanism by which it alleviates symptoms of Friedreich's ataxia is not fully understood, it is believed to help prevent further nervous system damage. Common side effects may include headache, nausea, stomach pain, and elevated liver enzyme levels. Always consult with a healthcare professional before starting any new medication.
Our Skyclarys coupons are free to use. You can print the coupon, email it to yourself, or receive the Skyclarys coupon via text message. To get your free discount, show the pharmacist your Skyclarys savings card which has the discounted coupon price. Use our filters below to edit the prescription box to match your needs. The Skyclarys prices will update based on your prescription needs. Above our Skyclarys coupons, you can change the location to see pharmacy prices in other areas. Our prescription discount card will update online with the specific pharmacy costs associated with your edits. Be sure to text, email, or print the Skyclarys savings card code that you need after editing the prescription box and location field. Show the discount card to your pharmacist before paying.

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50MG, Skyclarys (30 Capsules)

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Rite Aid

$10956.52

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$11419.91

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Skyclarys savings card

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Rite Aid

$10956.52

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Skyclarys dosage forms

The average cost for 30 Capsules of Skyclarys at 50MG is $10776.15 with a free coupon. This is 27.94% off the average retail price of $38563.03
DosageQuantityPrice fromPer unit
50MG30 Capsules$10776.15$359.2

Skyclarys Warnings

The following safety information outlines important warnings related to the use of Skyclarys (omaveloxolone). It is crucial to understand these risks and discuss any concerns with your healthcare provider.

  • Liver Health: Skyclarys (omaveloxolone) may increase liver enzyme levels, indicating potential liver damage. Regular blood tests before and during treatment are necessary to monitor liver function. Although most individuals do not experience symptoms, be vigilant for signs such as abdominal swelling, pain, yellowing of the skin or eyes, changes in stool color, dark urine, or confusion. Seek immediate medical attention if these occur, as cessation of the medication may be required to prevent further liver damage.

  • Heart Function: This medication can elevate brain natriuretic peptide (BNP) levels, which may signal heart failure – a common issue in individuals with FA. It is unclear if raised BNP levels are directly caused by the medication or underlying heart conditions. Notify your healthcare provider if you have a history of heart failure or experience symptoms like shortness of breath, swelling in the extremities, irregular heartbeat, difficulty with exercise, fatigue, or rapid weight gain.

  • Cholesterol Levels: Skyclarys (omaveloxolone) has the potential to increase cholesterol levels, typically observed within two weeks of starting treatment, but these levels usually normalize within a month after discontinuation. Your healthcare provider will monitor your cholesterol levels before and during treatment and may prescribe medication to help manage cholesterol if necessary.

In case of an overdose, immediately seek emergency medical assistance. Always follow your healthcare provider's guidance when using Skyclarys (omaveloxolone) and report any unusual symptoms or concerns promptly.

Skyclarys Side Effects

When taking this medication, some individuals may experience common side effects such as nausea, diarrhea, stomach pain, headache, fatigue, and mild increases in liver lab results. Additionally, some people may report bone, muscle, or joint pain, as well as mouth or throat discomfort. These effects are generally mild, but if they persist or worsen, it is advisable to consult your healthcare provider.

Other reported side effects include flu-like symptoms, vomiting, decreased appetite, muscle spasms, back pain, and skin rash. While less common, they should still be discussed with your healthcare provider if they occur.

There are more serious side effects to be aware of, although they are rare. Signs of liver damage, such as persistent nausea, vomiting, yellowing of the skin or eyes, dark urine, or abdominal pain, are serious and require immediate medical attention. Heart-related issues, like an irregular or pounding heartbeat, shortness of breath, sudden weight gain, or swelling in the legs, ankles, or feet, also warrant urgent medical care. Severe allergic reactions are infrequent but can include symptoms such as rash, severe dizziness, or difficulty breathing, and require prompt medical intervention.

Remember, this is not an exhaustive list of potential side effects. If you experience any unexpected reactions, it is important to contact your healthcare provider for further advice.

Skyclarys Interactions

This medication can reduce the effectiveness of hormonal birth control methods, including pills, patches, or rings, which may lead to pregnancy. It is important to talk to your doctor or pharmacist about using an additional reliable form of birth control while taking this medication and for 28 days after your last dose. Additionally, if you notice any new spotting or breakthrough bleeding, inform your doctor as these could indicate that your birth control is not working effectively.
Skyclarys FAQs
What is Skyclarys used for?

Skyclarys is used for the treatment of Friedreich's ataxia, a rare genetic disorder that affects the nervous system and movement.

The cost of Skyclarys can vary depending on factors such as insurance coverage, pharmacy pricing, and location. It is recommended to contact a local pharmacy or healthcare provider for the most accurate and up-to-date pricing information. Additionally, patients may inquire about patient assistance programs or insurance coverage options that could help reduce the cost.

Yes, Skyclarys is considered a specialty drug. Specialty drugs are typically used to treat complex or rare conditions and often require special handling, administration, or monitoring.

Skyclarys (omaveloxolone) is a medication approved for the treatment of Friedreich's ataxia, a rare genetic disorder. Clinical trials have shown that Skyclarys can improve neurological function in patients with this condition. The effectiveness can vary among individuals, and it is important for patients to discuss with their healthcare provider to understand how it may benefit their specific situation.

Yes, Skyclarys (omaveloxolone) is approved by the FDA. It was approved in February 2023 for the treatment of Friedreich's ataxia in adults and adolescents aged 16 years and older.

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