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When taking this medication, you may experience some common side effects such as drowsiness, dizziness, headache, constipation, upset stomach, blurred vision, decreased coordination, or dryness in the mouth, nose, or throat. These effects are generally mild, but if they persist or worsen, it is important to seek advice from your healthcare provider. To minimize dizziness and lightheadedness, try rising slowly from sitting or lying down.

While many individuals do not experience serious side effects, it's crucial to be aware of those that require prompt medical attention. Serious side effects can include changes in mental state or mood, such as hallucinations, irritability, nervousness, or confusion, as well as ringing in the ears, difficulty urinating, unusual bruising or bleeding, and a fast or irregular heartbeat. If any of these symptoms occur, contact your doctor immediately.

In rare instances, very serious side effects may arise, such as seizures, which necessitate immediate medical intervention. Additionally, although rare, allergic reactions can occur. Seek emergency help if you experience symptoms like rash, itching, swelling (particularly of the face, tongue, or throat), severe dizziness, or trouble breathing.

Please note this is not an exhaustive list of side effects. If you notice any other unusual symptoms, consult your doctor or pharmacist for further guidance.

Some medications and products can interact with this drug, potentially affecting how it works or increasing side effects. These include skin-applied antihistamines like diphenhydramine cream, ointment, or spray. Inform your healthcare provider if you are using any other substances that could cause drowsiness. This includes opioid pain or cough medications (such as codeine, hydrocodone), alcohol, marijuana, sleep or anxiety medications (like alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), and other antihistamines (like cetirizine, diphenhydramine).

It is important to read the labels on all your medications, especially those for allergies or cough-and-cold, as they may contain ingredients that induce drowsiness. Consult with your pharmacist for guidance on safe use of these products.

Additionally, this drug may interfere with certain laboratory tests, such as urine drug screenings, potentially leading to incorrect results. Ensure all your doctors and laboratory staff are aware that you are taking this medication.