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When taking aripiprazole in conjunction with other medications for depression, ensure that you thoroughly review the drug information for each medication involved. It is important to be aware that older adults with dementia who use this medication may face a slightly increased risk of severe, potentially life-threatening side effects, including stroke, heart failure, irregular heartbeat, and pneumonia. Aripiprazole is not approved for addressing behavioral issues related to dementia. It is crucial to have a detailed discussion with your doctor about the potential risks and benefits of using this medication, as well as considering alternative treatments that might be more effective and safer for managing dementia-related behavior problems.

Key points to consider:

• Carefully read the drug information for all medications involved when using aripiprazole for depression treatment.
• Be aware of the increased risk of severe side effects in older adults with dementia.
• Aripiprazole is not approved for dementia-related behavior problems.
• Discuss with your doctor the risks, benefits, and alternative treatment options.

When taking this medication, you may experience some common side effects such as dizziness, lightheadedness, drowsiness, nausea, vomiting, tiredness, excess saliva, drooling, blurred vision, weight gain, constipation, headache, and trouble sleeping. While these are generally mild, it's important to be cautious as dizziness and lightheadedness can increase your risk of falling. To minimize this risk, rise slowly from sitting or lying positions.

It's crucial to be aware of more serious side effects, which require immediate medical attention. These include fainting, significant mental or mood changes (such as increased anxiety, depression, or suicidal thoughts), trouble swallowing, restlessness (especially in the legs), shaking or tremors, muscle spasms, facial expression changes, seizures, and difficulty controlling certain impulses like gambling or eating.

Moreover, this medication may rarely lead to an increase in blood sugar levels, potentially exacerbating diabetes. If you notice symptoms such as increased thirst or urination, inform your doctor promptly. Additionally, there's a rare risk of developing tardive dyskinesia, a potentially permanent condition characterized by unusual uncontrolled movements.

Another rare but severe risk is neuroleptic malignant syndrome (NMS), presenting with symptoms like fever, muscle stiffness, severe fatigue, confusion, sweating, irregular heartbeat, dark urine, and signs of kidney issues. Seek immediate medical help if you experience these.

Lastly, though very rare, serious allergic reactions can occur, with symptoms including fever, swollen lymph nodes, rash, severe dizziness, and difficulty breathing. Always consult your doctor if you notice any unusual symptoms. This list is not exhaustive, so any new or worsening symptoms should be discussed with your healthcare provider.