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This medication contains acetaminophen and diphenhydramine, which can pose significant risks if not used properly. Below are important safety guidelines and warnings to ensure safe usage:

• Liver Health Risks: Excessive intake of acetaminophen can lead to severe, potentially fatal liver damage. Adults should not exceed 4000 milligrams (4 grams) of acetaminophen daily, and individuals with liver issues or children should follow stricter limits as advised by their healthcare provider. It's crucial to check all medications for acetaminophen content and consult your doctor or pharmacist before using multiple products containing acetaminophen. Drinking alcohol while taking acetaminophen can further harm the liver, so it should be avoided.

• Medication Interactions: Tylenol PM Extra Strength, which contains both acetaminophen and diphenhydramine, should not be used in conjunction with other medications containing these substances to prevent accidental overdose. Consult a healthcare provider before starting any new medications while using this product, as multiple sources of these ingredients can lead to serious side effects such as liver failure or seizures.

• Effects on Alertness: Diphenhydramine can cause significant drowsiness, affecting concentration and reaction times. This effect is heightened in individuals over 65, those consuming alcohol, or those taking other sedative medications. Avoid driving or operating machinery until you know how this medication impacts you.

• Pre-existing Conditions: Inform your healthcare provider of any medical conditions, such as liver problems, glaucoma, or respiratory issues, as these may worsen with the use of this medication. It is essential not to take this product if you have these conditions unless advised by your healthcare provider.

• Allergic Reactions: Though rare, serious skin reactions like rashes or blistering can occur. Discontinue use and seek medical attention immediately if you experience these symptoms.

• Emergency Overdose Actions: In cases of acetaminophen overdose, seek medical help immediately, even if symptoms are not present. Symptoms to watch for include nausea, vomiting, fatigue, and jaundice.

For any concerns or questions about using this medication safely, please consult with your healthcare provider.

When taking this medication, you may experience some common side effects such as dizziness, drowsiness, dry mouth, constipation, and stomach upset. These effects are generally mild and should not cause concern unless they persist or worsen, in which case consulting a healthcare provider is advisable. Blurred vision and headaches have also been reported, and while they are not uncommon, they should be monitored if they become problematic.

In rare instances, more serious side effects can occur. These include mental or mood changes like confusion, and difficulty urinating. It is important to seek medical advice promptly if you encounter any of these issues. Additionally, while very serious allergic reactions are rare, immediate medical help is necessary if you experience symptoms such as rash, itching or swelling of the face, tongue, or throat, severe dizziness, or trouble breathing.

There are also severe side effects that, although infrequent, require urgent medical attention. These include serious skin reactions like reddening, blisters, or a rash, as well as signs of liver damage such as severe stomach pain, yellowing of the skin or eyes, nausea, vomiting, or loss of appetite. Overdosing on this medication can lead to symptoms such as tiredness, flushed skin, warmth, vision changes, and confusion, necessitating immediate medical care. Always be vigilant about any additional side effects not listed here and contact your healthcare provider if they arise.