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This section provides essential safety information about the potential risks and precautions associated with Altoprev (lovastatin). It is crucial to review these points carefully and seek advice from your healthcare provider if you have any concerns.

• Severe Muscle Pain and Damage: Altoprev (lovastatin) can lead to a serious condition called rhabdomyolysis, which may result in kidney damage. The risk increases if you are taking other medications that elevate Altoprev levels or also cause muscle damage. Immediate medical attention is necessary if you experience symptoms such as intense muscle pain, tenderness, weakness, dark urine, or fatigue. Risk factors include being over 65 years old, high doses of Altoprev, kidney issues, and use of interacting medications.

• Liver Issues: Some users of Altoprev (lovastatin) have experienced changes in liver enzyme levels, indicating potential liver damage. Although rare, serious liver problems leading to liver failure can occur. Those with a history of liver issues or who consume large amounts of alcohol are at greater risk.

• Increased Blood Sugar Levels: Statins like Altoprev have been linked to increased blood sugar and hemoglobin A1C levels. Despite this, healthcare professionals generally consider the benefits of statins to outweigh these risks. If you have diabetes or high blood sugar, inform your provider prior to starting Altoprev. You may need to monitor your blood sugar more frequently and should maintain a healthy diet and regular exercise routine. The risk is heightened for individuals with high blood sugar.

• Pregnancy and Breastfeeding Risks: Altoprev (lovastatin) is usually not recommended during pregnancy or breastfeeding due to potential harm to the unborn or breastfed child. Discuss safe alternatives with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.

Contraindications: This medication should not be used in certain conditions due to serious health risks. Consult your healthcare provider if any of these apply to you:

• Use of specific medications that interact with Altoprev (lovastatin).
• Existing liver conditions such as liver failure or severe cirrhosis.
• Being currently pregnant or breastfeeding.

When taking this medication, it's important to be aware of the possible side effects, which range from common to rare and serious. Common side effects include infection, headaches, back pain, joint pain, and flu-like symptoms. These are generally mild but consult your healthcare provider if they persist or worsen.

Some users may experience muscle-related issues such as pain, tenderness, or cramps, as well as dizziness, diarrhea, urinary tract infections, or sinus infections. While these side effects are not uncommon, it's advisable to discuss them with your healthcare provider if they occur.

Rare but serious side effects require immediate medical attention. These include severe muscle damage, characterized by dark brown urine, severe muscle weakness or pain, fever, and extreme tiredness. Additionally, liver problems can manifest as yellowing of the skin or eyes, abdominal swelling, dark urine, and confusion. Although very uncommon, allergic reactions may occur, presenting as rash, itching, swelling, severe dizziness, or trouble breathing. If you experience these symptoms, seek urgent medical care.

Lastly, a very small number of individuals may face mild memory problems or confusion, and in rare cases, statins can affect blood sugar levels, potentially worsening diabetes. It's crucial to weigh the benefits and risks with your healthcare provider. If you notice other side effects not mentioned here, contact your healthcare provider promptly.

When taking Altoprev (Lovastatin), it is important to be aware of potential interactions with other medications or supplements. Inform your doctor and pharmacist about all the medications, vitamins, and herbal supplements you use. This is crucial as some substances can change how Altoprev works or increase the risk of side effects.

Certain drugs should not be used with lovastatin. These include blood thinners like Warfarin, and a range of other medications such as daptomycin, and Gemfibrozil. Additionally, medications that may affect how lovastatin is cleared from your body, such as azole antifungals (e.g., Itraconazole, Ketoconazole), cobicistat, Colchicine, Cyclosporine, and macrolide antibiotics (e.g., Clarithromycin, Erythromycin) should be avoided. HIV protease inhibitors like lopinavir and Ritonavir, as well as telithromycin, also fall into this category.

In some cases, your doctor may prescribe lovastatin alongside other medications even if there are potential interactions. If so, the doctor may adjust the dose or frequency to minimize risk. Such medications include Amiodarone, colchicine, cyclosporine, daptomycin, gemfibrozil, and others like Verapamil and diltiazem.

There are also medications that, when used with lovastatin, may increase the risk of side effects but might be necessary for your treatment. If prescribed together, your doctor will carefully manage your treatment regimen. These medications include Azithromycin, Clopidogrel, and supplements like St John's Wort.

Finally, avoid Red Yeast Rice products while on lovastatin, as they may also contain lovastatin, increasing the risk of serious muscle and liver problems. Always consult with your healthcare provider for advice tailored to your specific situation.