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The following safety information outlines the potential risks and precautions associated with the use of Amzeeq (minocycline topical foam). Please review this information carefully and discuss any concerns with your healthcare provider.

• Fire Hazard: Amzeeq contains a propellant that makes it highly flammable. Handle with care during and after use. Do not store the canister in temperatures exceeding 120°F. Avoid puncturing or exposing the canister to open flames. Refrain from smoking during and after application.

• Antibiotic Resistance: This medication is not approved by the FDA for treating bacterial infections. Using it for infections may worsen your condition and lead to antibiotic resistance. Only use Amzeeq for acne as directed by your healthcare provider.

• Risk of New Infections: Misuse of Amzeeq can result in the overgrowth of bacteria or fungi, potentially causing new infections such as yeast infections. Report any symptoms like itching, burning, or rash to your healthcare team and adhere to the prescribed duration of use.

• Sunburn and Skin Reactions: Minocycline, like other tetracycline antibiotics, can cause skin-related side effects, including increased sunburn risk and skin discoloration. Take precautions when exposed to sunlight.

• Pediatric Bone Development: Use of tetracycline antibiotics, including minocycline, can impact bone growth in children. Although it's unclear if Amzeeq has this effect, it should not be used by children under 9 years old.

• Rare Side Effects: Although not linked to Amzeeq, oral minocycline has been associated with serious side effects such as infectious diarrhea, liver issues, and neurological conditions. Consult your healthcare provider if you have any concerns.

Contraindications:

• Allergy Warning: Do not use Amzeeq if you have an allergy to tetracycline antibiotics. Always seek medical advice before starting the medication if this applies to you.

Ensure you're informed about these safety details and consult with a healthcare professional for personalized advice.

When using this medication, you may experience some common side effects such as skin redness, dryness, or itching. These are generally mild and often diminish over time. There might also be darkening of the skin in the area where the medication is applied. If these effects persist or worsen, it is advisable to consult a healthcare professional.

In rare cases, more serious side effects can occur. These include joint pain or swelling, and signs of kidney or liver problems, such as changes in urine output, loss of appetite, stomach pain, yellowing of the skin or eyes, and dark urine. Some users may also notice discoloration of the skin, scars, lips, gums, or teeth.

Occasionally, a severe intestinal condition caused by C. difficile bacteria may develop, potentially during treatment or even weeks afterward. Symptoms to watch for include persistent diarrhea, abdominal pain, and blood or mucus in the stool. Avoid using anti-diarrhea products in such cases, as they can worsen symptoms.

Other rare side effects include oral thrush or a new yeast infection, noticeable as white patches in the mouth or changes in vaginal discharge. Minocycline may also lead to increased pressure around the brain, with symptoms like a severe headache, vision changes, or persistent nausea and vomiting. This is more common in women of childbearing age who are overweight or have a history of intracranial hypertension.

A very serious allergic reaction is rare but requires immediate medical attention. Symptoms include fever, rash, itching, swelling of the face or throat, severe dizziness, and difficulty breathing. Always seek urgent care if you experience any severe side effects.