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Avanafil, marketed under the brand name Stendra, is used to address erectile dysfunction (ED) in men. This medication, which falls under the category of phosphodiesterase 5 (PDE5) inhibitors, functions by blocking the PDE5 protein. This blockage facilitates the relaxation of certain blood vessels, enhancing blood flow to the penis and aiding in achieving and maintaining an erection when combined with sexual stimulation. For optimal results, it is advised to take Avanafil approximately 15 to 30 minutes prior to engaging in sexual activity, limited to once per day. Common side effects may include headaches and flushing. It is important to note that Avanafil does not offer protection against sexually transmitted diseases such as HIV or hepatitis B. To minimize the risk of infection, the use of effective barrier methods, like latex or polyurethane condoms, is recommended during all sexual activities. For personalized advice, please consult your healthcare provider.