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When taking avanafil, you might experience mild side effects such as headache, flushing, or dizziness. These are generally not a cause for concern, but if they persist or worsen, you should inform your healthcare provider. To minimize dizziness and lightheadedness, try standing up slowly from a sitting or lying position.

While using this medication, some people may experience more serious side effects. During sexual activity, if you have heart issues and encounter severe dizziness, fainting, chest, jaw, or left arm pain, or nausea, seek medical assistance immediately. Rarely, avanafil can cause a sudden decrease in vision, including permanent blindness (NAION). This risk is slightly higher if you have certain conditions such as heart disease, diabetes, high cholesterol, specific eye problems, high blood pressure, are over 50, or smoke. If you notice these symptoms, stop taking the medication and consult a healthcare professional right away.

Additionally, avanafil can occasionally lead to a sudden loss of hearing, sometimes accompanied by ringing in the ears and dizziness. If this occurs, discontinue use and seek medical attention. Another rare but serious condition is a painful or prolonged erection lasting four or more hours, which requires immediate medical intervention to prevent permanent damage.

Although a severe allergic reaction to avanafil is uncommon, it is crucial to get medical help if you experience symptoms like rash, itching, swelling (particularly of the face, tongue, or throat), severe dizziness, or difficulty breathing. If you observe any side effects not mentioned, contact your healthcare provider for guidance.