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The use of this medication involves important safety considerations that must be taken into account to prevent potential health risks. Below are key warnings and precautions to ensure safe use:

• Risk to Unborn Babies: This medication can cause serious harm to an unborn child, potentially leading to life-threatening conditions. It is crucial not to take this medication during pregnancy. The drug may impact the development and function of the unborn baby's kidneys. Those who are pregnant, planning to become pregnant, or suspect pregnancy should immediately inform their healthcare provider. Additionally, effective birth control methods should be discussed and used while on this medication.

• Low Blood Pressure: Candesartan (Atacand) can occasionally cause a significant drop in blood pressure, leading to dizziness, tiredness, or lightheadedness. These symptoms are more likely at the beginning of the treatment or when the dosage is increased. The risk is heightened if you are dehydrated or have conditions that cause dehydration, such as prolonged diarrhea or vomiting, or are on high doses of diuretics.

• Kidney Damage: While candesartan (Atacand) is sometimes used to protect kidney function, it can also impair kidney performance. This adverse effect may be more severe in individuals with existing severe heart failure, certain kidney issues, or those taking other medications that can harm the kidneys.

• High Potassium Levels: The use of candesartan (Atacand) can lead to elevated potassium levels, particularly if taken alongside other medications known to increase potassium, like spironolactone (Aldactone) or eplerenone (Inspra). Symptoms such as nausea, muscle weakness, or irregular heartbeat should be reported to a healthcare provider promptly as unchecked high potassium can be dangerous.

• Contraindications: This medication should not be used concurrently with aliskiren (Tekturna) in individuals with diabetes due to the risk of serious health complications.

• Emergency Measures: In the event of an overdose or severe reaction, immediate medical attention is necessary. Contact emergency services or head to the nearest hospital.

For any concerns or further clarification, it is essential to consult with a healthcare professional. Always adhere to prescribed dosages and follow medical advice closely to ensure safety and effectiveness.

Common side effects:

• Dizziness
• Tiredness
• Lightheadedness
• Runny nose
• Sore throat
• Symptoms resembling a common cold

Less common but important to monitor:

• Back pain
• Stuffy nose

Serious side effects:

• Muscle weakness
• Irregular heartbeat
• Reduced urination
• Swelling in the limbs
• Severely low blood pressure
• Extreme dizziness
• Fainting
• Confusion
• Rash
• Itching
• Severe dizziness
• Difficulty breathing

Interactions with high risk of serious adverse effects and should be avoided:

• Aliskiren
• Lithium
• ACE inhibitors (e.g., Benazepril, Lisinopril, Captopril, Enalapril, Enalaprilat, Fosinopril, Moexipril, Perindopril, Quinapril, Ramipril, Trandolapril)

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Drugs that increase potassium levels (e.g., Sparsentan)
• Birth control pills containing Drospirenone
• NSAIDs (e.g., Ibuprofen, Naproxen, Bromfenac, Bufexamac, Celecoxib, Choline Salicylate, Clonixin, Dexibuprofen, Dexketoprofen, Diclofenac, Diflunisal, Dipyrone, Droxicam, Etodolac, Etofenamate, Etoricoxib, Felbinac, Fenoprofen, Fepradinol, Feprazone, Floctafenine, Flufenamic Acid, Flurbiprofen, Indomethacin, Ketoprofen, Ketorolac, Lornoxicam, Loxoprofen, Lumiracoxib, Meclofenamate, Mefenamic Acid, Meloxicam, Morniflumate, Nabumetone, Nepafenac, Niflumic Acid, Nimesulide, Nimesulide Beta Cyclodextrin, Oxaprozin, Oxyphenbutazone, Parecoxib, Phenylbutazone, Piketoprofen, Piroxicam, Proglumetacin, Propionic Acid, Propyphenazone, Proquazone, Rofecoxib, Salicylic Acid, Salsalate, Sodium Salicylate, Sulindac, Tenoxicam, Tiaprofenic Acid, Tolfenamic Acid, Tolmetin, Valdecoxib)