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Cevimeline

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generic Evoxac

This medication is used to treat symptoms of dry mouth due to a certain immune disease (Sjogren's syndrome). Cevimeline belongs to a class of drugs known as cholinergic agonists. It works by stimulating certain nerves to increase the amount of saliva you produce, making it easier and more comfortable to speak and swallow.
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30MG, Cevimeline (30 Capsules)

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CVS

$32.46

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$24.24

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$25.18

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$34.62

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$49.25

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Cevimeline Side Effects

Sweating, nausea, runny nose, flushing, frequent urge to urinate, dizziness, weakness, diarrhea, and blurred vision may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. This medication may cause an increase in tears. This can be helpful if you have dry eyes. Tell your doctor if runny eyes become a problem. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: slow/fast/irregular heartbeat, shakiness (tremor), fainting, lung problems (such as increased wheezing/cough/phlegm), mental/mood changes (such as confusion, agitation), severe stomach/abdominal pain. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Interactions

Some products that may interact with this drug include: beta blockers (such as metoprolol, atenolol). Other medications can affect the removal of cevimeline from your body, which may affect how cevimeline works. Examples include cimetidine, amiodarone, ritonavir, fluoxetine, among others.
Cevimeline FAQs
What is the drug cevimeline used for?

Cevimeline is used to treat symptoms of dry mouth in individuals with Sjgren's syndrome. It works by stimulating the salivary glands to produce more saliva.

Cevimeline and pilocarpine are both medications used to treat dry mouth, particularly in patients with Sjgren's syndrome. The primary difference between them lies in their chemical structure and receptor selectivity. Cevimeline is a selective muscarinic receptor agonist, primarily targeting the M1 and M3 receptors, which are involved in stimulating salivary gland secretion. Pilocarpine, on the other hand, is a non-selective muscarinic receptor agonist, affecting a broader range of muscarinic receptors. This difference in selectivity can influence their side effect profiles and efficacy in individual patients.

A likely side effect of cevimeline is excessive sweating. Other common side effects may include nausea, diarrhea, and increased salivation.

Cevimeline is primarily used to treat symptoms of dry mouth in patients with Sjgren's syndrome. While it is not specifically indicated for dry eyes, some patients with Sjgren's syndrome may experience an improvement in dry eye symptoms as a secondary effect due to increased overall moisture production. However, it is important for patients to consult with their healthcare provider for appropriate treatment options for dry eyes.

Pilocarpine is most commonly used for the treatment of glaucoma. It helps to reduce intraocular pressure in the eye.

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