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When taking this medication, it is crucial to be aware of potential interactions and exercise necessary precautions. Here are some important points to consider:

• Drug Interactions: Be cautious of other products that may interact with this medication, including topical antihistamines like diphenhydramine creams, ointments, or sprays. Inform your doctor or pharmacist if you are using any products that may cause drowsiness, such as:

  • Opioid pain relievers or cough suppressants (e.g., codeine, hydrocodone)
  • Alcohol and marijuana (cannabis)
  • Medications for sleep or anxiety (e.g., alprazolam, lorazepam, zolpidem)
  • Muscle relaxants (e.g., carisoprodol, cyclobenzaprine)
  • Other antihistamines (e.g., cetirizine, diphenhydramine)

• Medication Labels: Review the labels on all your medications, including those for allergies or cough-and-cold, as they may contain ingredients that induce drowsiness. Consult your pharmacist to ensure safe usage.

• Similar Medications: Avoid using medications containing dexchlorpheniramine while taking this drug, as chlorpheniramine is very similar.

• Laboratory Interference: This medication can interfere with certain laboratory tests, such as allergy skin testing, potentially leading to inaccurate results. Ensure that all laboratory personnel and your healthcare providers are informed that you are using this medication.

Adhering to these guidelines will help you manage your treatment safely and effectively. Always consult your healthcare professional for personalized advice.

Common side effects:

• drowsiness
• dizziness
• constipation
• stomach upset
• blurred vision
• dry mouth
• dry nose
• dry throat

Less common but important to monitor:

• mental or mood changes
• difficulty urinating
• fast or irregular heartbeat

Serious side effects:

• seizures
• severe allergic reaction
• rash
• itching or swelling
• severe dizziness
• trouble breathing

Interactions with high risk of serious adverse effects and should be avoided:

• Dexchlorpheniramine

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Opioid pain relievers (e.g., codeine, hydrocodone)
• Alcohol
• Marijuana (cannabis)
• Medications for sleep or anxiety (e.g., Alprazolam, Lorazepam, Zolpidem)
• Muscle relaxants (e.g., Carisoprodol, Cyclobenzaprine)
• Other antihistamines (e.g., Cetirizine, diphenhydramine)

Interactions with low risk that usually do not require a change in therapy:

• Skin-applied antihistamines (e.g., diphenhydramine cream, ointment, spray)