HomeConditionsFolate Deficiency

Folate Deficiency

Folate Deficiency: Causes, Symptoms, and Treatment. Learn about the importance of folate and how its deficiency can lead to various health problems. Discover the causes, symptoms, and treatment options for folate deficiency, and find out how to prevent it through diet and supplementation.

Best medications for Folate Deficiency

Drug NameClassRouteStandard DosagePrice
Folic AcidFolate AnaloguesOral1000-200, 150-1.25, 400, 324-1, 8.333-100-1, 0.8, 1-2000, 1, 20, 1-3760, 800, 2.5-25-1, 2000-200, 1-10000, 60-1.25, 1342-1, 27-0.8-200, 0.8-50-0.1, 1-3800, 5.1-35-2, 0.8-10-0.115, 1-5750, 1-3775, 35-1, 0.4-50-0.1, 100-1000-15, 2.2-25-1, 500-400, 1-5000, 90-120-0.012-1, 12-1, 2.3-24.5-2, 2500-400, 5, 90-1, 0.5-5-0.2, 2.2-25-0.5, 1-75, 500-5-200, 0.9, 100-250-0.025-1from$13.38
SafyralEstrogen / Progestin / Folate CombinationsOral3-0.03-0.451 MGfrom$53.85
BeyazEstrogen / Progestin / Folate CombinationsOral3-0.02-0.451 MGfrom$44.91
L-methylfolate CalciumFolate AnaloguesOral7.5, 15 MGfrom$31.16
L-MethylfolateFolate AnaloguesOral3-90.314-2-35, 15-90.314, 1.13-25-2, 7.5-90.314, 15, 6-90.314-2-600, 6-1-50-5, 7.5, 15-2, 3-35-2 MGfrom$31.16
DenovoMultivitamin and Mineral SupplementsOral15, 15-2 MGfrom$0.00
Fusion PlusMultivitamin and Mineral SupplementsOralfrom$31.19
Vitranol FEMultivitamin and Mineral SupplementsOralfrom$833.86
Venexa FeMultivitamin and Mineral SupplementsOralfrom$1581.46
Folitin-ZMultivitamin and Mineral SupplementsOralfrom$722.22


Folate, also known as vitamin B9, is an essential nutrient that plays a vital role in various bodily functions. It helps in the production of red blood cells, DNA synthesis, and cell division. Folate is especially important during pregnancy as it aids in the proper development of the baby's neural tube. A deficiency in folate can lead to numerous health problems and should be addressed promptly. In this article, we will explore the causes, symptoms, and treatment options for folate deficiency.

Causes of Folate Deficiency

There are several factors that can contribute to a deficiency in folate. Inadequate dietary intake is one of the primary causes. Folate is predominantly found in leafy green vegetables, fruits, legumes, and fortified grains. Individuals who do not consume enough of these foods may be at risk of developing a deficiency. Additionally, certain medical conditions such as malabsorption disorders, alcoholism, kidney dialysis, and inflammatory bowel disease can interfere with folate absorption and utilization.

Symptoms of Folate Deficiency

Folate deficiency can manifest in various ways, and the symptoms may vary depending on the severity of the deficiency. Common signs include fatigue, weakness, pale skin, shortness of breath, and headaches. Individuals with folate deficiency may also experience difficulty concentrating, irritability, and depression. In severe cases, the deficiency can result in glossitis (inflammation of the tongue), diarrhea, and even neural tube defects in infants if the deficiency occurs during pregnancy.

Treatment of Folate Deficiency

The treatment for folate deficiency primarily involves increasing the intake of folate-rich foods or taking folic acid supplements. These supplements are readily available over-the-counter and are safe for most individuals. Pregnant women or individuals with severe deficiencies may require higher doses of supplements under the guidance of a healthcare professional. Additionally, addressing the underlying cause of the deficiency, such as treating malabsorption disorders or managing alcoholism, is crucial to prevent recurrence.

Prevention of Folate Deficiency

Preventing folate deficiency can be achieved through a well-balanced diet that includes foods rich in folate. Incorporating leafy green vegetables, citrus fruits, beans, and whole grains into daily meals is recommended. For pregnant women, prenatal vitamins containing folic acid are typically prescribed to reduce the risk of neural tube defects in the developing baby. It is essential to consult a healthcare provider for personalized advice regarding folate intake, especially for individuals with specific medical conditions or dietary restrictions.


Folate deficiency is a common nutritional deficiency that can have significant consequences for overall health, particularly during pregnancy. It is essential to ensure an adequate intake of folate through a balanced diet or appropriate supplementation. Recognizing the causes and symptoms of folate deficiency and seeking appropriate treatment can help prevent complications and improve overall well-being. If you suspect a folate deficiency or have concerns, it is always best to consult with a healthcare professional for proper evaluation and guidance.