HomeConditionsUterine Cancer

Uterine Cancer

Uterine cancer, also known as endometrial cancer, is a type of cancer that starts in the lining of the uterus. It is more common in women over 50 and is often linked to hormonal imbalances, obesity, and diabetes. Symptoms can include abnormal vaginal bleeding and pelvic pain. Treatment options include surgery, radiation therapy, and chemotherapy. Early detection is crucial for better outcomes.

Best medications for Uterine Cancer

Drug NameClassRouteStandard DosagePrice
TrexallAntifolatesOral7.5, 15, 5, 10 MGfrom$1267.85
Megestrol AcetateProgestinsOral400, 20, 625, 800, 40 MGfrom$7.65
HYDROXYprogesterone CaproateProgestinsIntramuscular1.25, 250, 275 MG/MLfrom$223.83
MethotrexateAntifolatesInjection2.5, 250, 17.5, 7.5, 1, 15, 22.5, 20, 1000, 10, 5, 25, 50, 12.5, 30 GMfrom$315.65
RozlytrekKinase InhibitorsOral200, 100 MGfrom$6736.19
VitrakviKinase InhibitorsOral25, 20, 100 MGfrom$19650.19

What is Uterine Cancer?

Uterine cancer, also known as endometrial cancer, is a type of cancer that begins in the lining of the uterus, called the endometrium. The uterus is a hollow organ located in the female reproductive system, where a fertilized egg implants and grows into a baby during pregnancy. Uterine cancer occurs when the cells in the endometrium grow abnormally, forming a tumor.

Types of Uterine Cancer

There are different types of uterine cancer, but the most common type is endometrial adenocarcinoma, accounting for the majority of cases. Other less common types include endometrial stromal sarcoma and uterine carcinosarcoma. The type and stage of uterine cancer can determine the treatment options and prognosis for patients.

Causes and Risk Factors

The exact cause of uterine cancer is still unknown, but certain risk factors can increase a woman's likelihood of developing the disease. These risk factors include:

1. Hormonal Factors

Hormonal imbalances, such as high levels of estrogen relative to progesterone, can increase the risk of uterine cancer. This hormonal imbalance can occur in women who have never been pregnant, those who started menstruating at an early age or experienced late menopause, and those who have polycystic ovary syndrome (PCOS).

2. Age and Menopause

Uterine cancer primarily affects women over the age of 50, with the average age of diagnosis being 60 years. The risk of developing uterine cancer increases with age, especially after menopause. Estrogen levels tend to be higher in women who have not yet reached menopause or who experience late menopause.

3. Obesity

Obesity is a significant risk factor for uterine cancer, mainly due to the increased production of estrogen by fatty tissues. Women with a body mass index (BMI) higher than 30 are at a higher risk of developing uterine cancer compared to those with a healthy weight.

4. Diabetes

Women with diabetes, especially type 2 diabetes, have a higher risk of developing uterine cancer. The link between diabetes and uterine cancer is thought to be related to high insulin levels and the accompanying hormonal imbalances.


The most common symptom of uterine cancer is abnormal vaginal bleeding, particularly postmenopausal bleeding or bleeding between periods. Other possible symptoms may include pelvic pain, pain during intercourse, difficulty urinating, or a watery or blood-tinged vaginal discharge.

Treatment Options

The treatment for uterine cancer depends on several factors, including the stage and type of cancer, as well as the patient's overall health. The main treatment options include:

1. Surgery

Surgery is the most common treatment for uterine cancer and typically involves the removal of the uterus (hysterectomy). In some cases, additional procedures may be necessary, such as the removal of the ovaries and fallopian tubes or nearby lymph nodes.

2. Radiation Therapy

Radiation therapy uses high-energy rays to kill cancer cells. It may be recommended before surgery to shrink tumors or after surgery to kill remaining cancer cells. In some cases, radiation therapy may be the primary treatment if surgery is not an option.

3. Chemotherapy

Chemotherapy involves the use of anti-cancer drugs to kill cancer cells or stop their growth. It is often recommended for advanced or recurrent uterine cancer or when the cancer has spread to other parts of the body.