Vitamin E does not usually cause side effects when used in recommended doses. However, vitamin E may cause side effects if taken at high doses (400 units or more per day) or for a long period of time. In these situations, nausea, diarrhea, stomach cramps, tiredness, dizziness, blurred vision, and headache may rarely occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: easy bleeding/bruising. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Some drugs that may interact with this product are: bile acid-binding resins (such as cholestyramine, colestipol), "blood thinners" (such as warfarin), iron supplements, mineral oil. If you are also taking orlistat, separate the time between orlistat and vitamin E doses by at least 2 hours. Check the labels on all your prescription and nonprescription/herbal products because they may contain vitamin E. Ask your doctor or pharmacist about using those products safely.