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You may experience mild side effects such as nausea, vomiting, headaches, bloating, breast tenderness, ankle or foot swelling due to fluid retention, and changes in weight. Minor vaginal bleeding between periods or irregular/missed periods might also occur, particularly in the initial months of use. These effects are generally not serious but if they persist or worsen, it is important to consult a healthcare professional. Additionally, monitor your blood pressure as this medication can cause an increase, and report any high readings to your healthcare provider.

For more serious side effects, prompt medical attention is crucial. These include lumps in the breast, significant changes in mood or mental health, severe abdominal pain, unusual vaginal bleeding, dark urine, or yellowing of the skin or eyes. Rarely, this medication can lead to life-threatening blood clot issues resulting in heart attacks, strokes, or clots in the lungs or legs. Immediate medical help is needed if symptoms such as chest pain, sudden dizziness, fainting, pain in the groin or calf, difficulty speaking, shortness of breath, severe headaches, sweating, weakness on one side of the body, or sudden vision changes occur.

Though rare, severe allergic reactions can happen. Seek urgent medical care if you experience symptoms like rash, significant itching or swelling, particularly of the face, tongue, or throat, severe dizziness, or trouble breathing. Remember, this is not an exhaustive list of potential side effects. If you encounter any other unusual symptoms, contact your healthcare provider for advice.

Certain medications can interact with this drug, including aromatase inhibitors (like Anastrozole and Exemestane), fezolinetant, ospemifene, Tamoxifen, Tizanidine, Tranexamic Acid, and some treatments for chronic hepatitis C (such as ombitasvir/paritaprevir/Ritonavir, with or without dasabuvir). Additionally, some drugs might reduce the effectiveness of hormonal birth control by lowering hormone levels, which could lead to pregnancy. These drugs include griseofulvin, Modafinil, rifamycins (like Rifampin and Rifabutin), ritonavir, St. John's wort, and certain seizure medications (such as barbiturates, Carbamazepine, Felbamate, Phenytoin, Primidone, and Topiramate), as well as some HIV medications (like nelfinavir and Nevirapine), among others.

It's important to inform your doctor when you begin any new medication and discuss whether you should use additional birth control methods. If you notice any unexpected spotting or bleeding, let your doctor know, as these could indicate that your birth control is not fully effective.

This medication might also affect certain laboratory tests, such as those for blood clotting factors or thyroid function, potentially leading to incorrect results. Ensure that all healthcare providers and laboratory staff are aware that you are taking this medication.