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This safety and warning information is essential for understanding the potential risks and necessary precautions when using this medication. Please read the following points carefully and consult your healthcare provider with any concerns:

• Medication Interactions: Inform your healthcare provider or pharmacist about all medications and supplements you are currently taking before beginning norethindrone. This will help to identify and manage any possible drug interactions.

• Ectopic Pregnancy or Ovarian Cyst: There is a small risk that if you become pregnant while taking norethindrone, the pregnancy could be ectopic, occurring outside the womb. This condition is serious. Seek immediate medical attention if you experience symptoms such as cramping or pain in the lower abdomen or shoulder.

• Irregular Vaginal Bleeding: Irregular vaginal bleeding is a common side effect of progestin-only pills (POPs) like norethindrone. In rare cases, it may indicate a more serious condition such as an infection or cancer. Consult your healthcare provider if you are concerned about irregular bleeding. If you do not experience any vaginal bleeding, check with your provider to rule out pregnancy.

• Possible Risk of Cancer: Some research indicates that combination birth control pills may increase the risk of breast or ovarian cancer. It is unclear whether norethindrone or other POPs carry the same risk. Discuss any concerns regarding cancer risks with your healthcare provider.

Contraindications: This medication should not be used under the following conditions due to potential serious health risks. Consult your healthcare provider if any of these apply to you:

• Pregnancy
• Confirmed or suspected breast cancer
• Undiagnosed bleeding between periods
• Liver tumors, whether benign or malignant
• Acute liver disease

For safe and effective use, it is important to adhere to these guidelines and seek professional medical advice as needed.

When taking this medication, some individuals may experience mild side effects, such as nausea, vomiting, headaches, bloating, breast tenderness, and weight gain. It's also common to experience changes in menstrual cycles, including spotting or irregular periods. If these symptoms persist or worsen, consult your healthcare provider for guidance.

In some cases, individuals may notice more significant changes, such as lumps in the breast, mood alterations like depression, severe abdominal pain, or unusual vaginal bleeding patterns. These should be reported to your healthcare provider promptly for further evaluation.

Although very rare, severe side effects like ectopic pregnancy, indicated by stomach pain and spotting, require immediate medical attention. Additionally, symptoms of a serious allergic reaction, such as rash, swelling, severe dizziness, or trouble breathing, necessitate urgent care.

Always stay vigilant about any new symptoms or changes in your health while taking this medication and seek medical advice as needed. This ensures that any potential concerns are addressed promptly and appropriately.