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Deplin FC™ is a medical food designed to support individuals with depression by providing L-methylfolate, the active form of folate. While generally well-tolerated, it's important to consider certain precautions to ensure its safe use.

Individuals with known hypersensitivity to L-methylfolate or any of the ingredients in Deplin FC™ should avoid using this product. Additionally, those with a history of vitamin B12 deficiency should consult their healthcare provider before starting Deplin FC™, as high doses of folate can mask the symptoms of vitamin B12 deficiency, potentially leading to neurological complications.

Pregnant or nursing individuals are advised to seek medical advice prior to using Deplin FC™ to ensure it aligns with their specific health needs. Furthermore, Deplin FC™ should be stored at room temperature, protected from heat, light, and moisture, and kept out of reach of children to maintain its efficacy and prevent accidental ingestion.

As with any medical food or supplement, it's crucial to use Deplin FC™ under the supervision of a healthcare provider to ensure it is appropriate for your individual health circumstances.

Deplin, containing l-methylfolate, is a medical food used to manage conditions like depression and folate deficiency. While generally well-tolerated, it's important to be aware of potential interactions with other medications:

• Anticonvulsants: Medications such as Carbamazepine, Oxcarbazepine, Eslicarbazepine, and Phenobarbital may lower folic acid levels in the body. Conversely, folic acid supplementation can reduce the blood levels of these anticonvulsants, potentially diminishing their effectiveness. If you're taking both Deplin and any of these anticonvulsants, your doctor may need to adjust dosages or monitor your condition more closely. Be vigilant for any changes in your health or seizure control and inform your healthcare provider promptly.

• Capecitabine: Combining Deplin with capecitabine, a chemotherapy drug, can enhance capecitabine's effects, increasing the risk of serious side effects like anemia, bleeding issues, infections, and nerve damage. Symptoms to watch for include severe nausea, vomiting, diarrhea, unusual fatigue, dizziness, unexplained bruising or bleeding, fever, chills, and numbness or tingling in the hands and feet. Immediate medical attention is necessary if you experience any of these symptoms.

• Vitamin B12: No known interactions exist between Deplin and Vitamin B12. However, it's always advisable to consult your healthcare provider before starting any new supplements.

Always inform your doctor about all medications, vitamins, and herbal supplements you're taking to ensure safe and effective treatment. Do not discontinue any prescribed medication without first consulting your healthcare provider.