HomeDrug ClassesCardiac Myosin Inhibitors

Cardiac Myosin Inhibitors: Uses, Common Brands, and Safety Info

Cardiac myosin inhibitors are a class of medications used to treat heart failure by inhibiting the enzyme cardiac myosin. While no brands are currently on the market, drugs like mavacamten and omecamtiv mecarbil are showing promise in clinical trials. Side effects are generally mild, but further research is needed to determine long-term safety and efficacy. These medications offer potential for improved treatment of heart failure.

Cardiac Myosin Inhibitors

Cardiac Myosin Inhibitors are a class of medications that are used for the treatment of certain heart conditions. These drugs work by selectively inhibiting cardiac myosin, an enzyme that plays a vital role in regulating the contraction of heart muscles. By inhibiting this enzyme, cardiac myosin inhibitors help to reduce the workload on the heart and improve its efficiency.


Cardiac Myosin Inhibitors are primarily used in the management of heart failure. Heart failure occurs when the heart is unable to pump blood effectively, leading to symptoms such as shortness of breath, fatigue, and fluid retention. These medications are prescribed to help improve the symptoms of heart failure and enhance the overall quality of life for affected individuals.

Common Brands

There are currently no cardiac myosin inhibitors available on the market, as these medications are still in the experimental stage of development. However, several drugs that belong to this class are being studied in clinical trials and show promising results. Some of these investigational drugs include mavacamten, CK-274, and omecamtiv mecarbil. It is important to note that these drugs are not yet approved for routine clinical use and should only be used under the supervision of a healthcare professional within the context of a clinical trial.


Since cardiac myosin inhibitors are not widely available, their safety profile is still being extensively evaluated in clinical trials. However, based on the available data so far, these medications are generally well-tolerated. Common side effects may include headache, dizziness, nausea, and fatigue. It is essential to keep in mind that individual responses to medications can vary, and patients should always consult their healthcare provider for personalized advice. As cardiac myosin inhibitors are a novel class of drugs, there is still much research to be done to determine their long-term safety and efficacy. Patients should only consider using these medications under the guidance of a healthcare professional who is knowledgeable about the latest research findings and can provide appropriate monitoring and supervision. Overall, cardiac myosin inhibitors hold great promise in the treatment of heart failure. As further studies are conducted and more information becomes available, these medications may offer new options for individuals living with this chronic condition.

List of Cardiac Myosin Inhibitors