HomeDrug ClassesOrthopoxvirus Inhibitor

Orthopoxvirus Inhibitor: Uses, Common Brands, and Safety Info

The article discusses the Orthopoxvirus Inhibitor drug class, focusing on its uses, common brands, and safety considerations. Tpoxx is highlighted as one of the well-known brands within this class. It emphasizes the importance of following prescribed dosage and duration, as well as the need for supervision by a healthcare professional when using these medications. The article concludes by highlighting the potential advancements in antiviral therapies for orthopoxvirus infections.


Orthopoxviruses are a family of viruses that can cause severe infections in humans, including the notorious smallpox virus. The development of effective treatment options against these viruses is of utmost importance to public health. That is where the drug class Orthopoxvirus Inhibitors comes into play. These inhibitors are specifically designed to target and inhibit the replication of orthopoxviruses, offering a potential therapeutic option for individuals infected with these viruses.


The primary use of Orthopoxvirus Inhibitors is the treatment of orthopoxvirus infections, including smallpox. Smallpox is a highly contagious disease that has been eradicated globally, primarily due to successful vaccination efforts. However, concerns about bioterrorism and the potential re-emergence of smallpox have prompted the development of antiviral treatments.

Common Brands

One commonly known brand name for an Orthopoxvirus Inhibitor is Tpoxx. Tpoxx (also known as Tecovirimat) is an oral medication that was approved by the U.S. Food and Drug Administration (FDA) in 2018 for the treatment of smallpox. It is the first drug to receive FDA approval specifically for this indication, making it an important advancement in the field of infectious disease management.


As with any medication, safety considerations should always be taken into account. It is essential to follow the prescribed dosage and duration when using Orthopoxvirus Inhibitors. These medications may have potential side effects, including gastrointestinal disturbances, headache, and fatigue, although they are generally well-tolerated. It is crucial to note that Orthopoxvirus Inhibitors, including Tpoxx, are advanced antiviral medications that are used in specific circumstances, such as during a smallpox outbreak or in cases of suspected bioterrorism. These drugs should only be used under the guidance and supervision of a qualified healthcare professional. In conclusion, Orthopoxvirus Inhibitors, such as Tpoxx, are an important drug class used for the treatment of orthopoxvirus infections, including smallpox. While Tpoxx is one well-known brand within this class, safety and proper usage should always be carefully considered. As advancements in antiviral therapies continue, the hope is to further expand treatment options and improve outcomes for individuals affected by orthopoxvirus infections.

List of Orthopoxvirus Inhibitor