Tpoxx Coupons & Savings Card – Discount Prices from $1.01
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200MG, Tpoxx (30 Capsules)
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CVS
$18.01
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Walmart
$1.01
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Walgreens
$2.00
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Albertsons
$9.51
COUPON PRICETpoxx savings card
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$1.01
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Price history for Tpoxx
30 Capsules, 200MG
Average retail price for Tpoxx
Average SaveHealth price for Tpoxx
Our price history data is based on aggregated prescription data collected from participating pharmacies in America. Our prescription data updates daily to reflect the latest price changes. If you notice a missing data point, it means there wasn't sufficient data available to generate a monetary value for that date.
*Retail prices are based on pharmacy claims data, and may not be accurate when we don't have enough claims.
Tpoxx dosage forms
| Dosage | Quantity | Price from | Per unit |
|---|---|---|---|
| 200MG | 30 Capsules | $1.01 | $0.03 |
Tpoxx Warnings
When considering the use of TPOXX (tecovirimat), it's important to be aware of certain risks and precautions:
Limited Human Efficacy Data: TPOXX's effectiveness against smallpox has been established through animal studies, as conducting human trials for this disease is not feasible. Therefore, its efficacy in humans is inferred from these animal models.
Use in Immunocompromised Individuals: Studies suggest that TPOXX may be less effective in individuals with weakened immune systems. This reduced efficacy has been observed in immunocompromised animal models, indicating potential concerns for similar human populations.
Intravenous (IV) Administration Concerns: The IV form of TPOXX contains hydroxypropyl-β-cyclodextrin, an ingredient cleared by the kidneys. In patients with severe renal impairment (creatinine clearance below 30 mL/min), this can lead to accumulation and potential toxicity. Consequently, TPOXX injection is contraindicated in these individuals. For those with mild to moderate renal impairment, close monitoring of kidney function is advised during treatment.
Potential for Viral Resistance: Overuse of TPOXX could lead to the development of viral resistance. Even minor mutations in the virus may render the drug less effective. Therefore, healthcare providers are encouraged to prescribe TPOXX judiciously to mitigate this risk.
Use During Pregnancy and Breastfeeding: There is limited data on the safety of TPOXX during pregnancy. Animal studies have not shown harm to the fetus, but it's unclear if these findings translate to humans. Additionally, it's unknown whether TPOXX passes into human breast milk. Given the potential for virus transmission through breastfeeding, it is generally not recommended for patients with smallpox to breastfeed during treatment.
Patients should discuss these risks with their healthcare provider to determine if TPOXX is appropriate for their specific situation.
Tpoxx Side Effects
TPOXX (tecovirimat) is an antiviral medication approved for the treatment of smallpox. While generally well-tolerated, some individuals may experience side effects. The most commonly reported side effects in healthy adults taking TPOXX capsules include headache (12%), nausea (5%), abdominal pain (2%), and vomiting (2%). For those receiving TPOXX via intravenous (IV) infusion, the most frequent side effects are reactions at the infusion site, such as pain (73%), swelling (39%), redness (23%), and extravasation (19%), along with headache (15%). In rare cases, TPOXX may cause low blood sugar (hypoglycemia), especially when taken with repaglinide, a medication used to treat type 2 diabetes. Symptoms of low blood sugar can include headache, dizziness, weakness, drowsiness, confusion, fast heartbeat, hunger, sweating, irritability, and feeling jittery or shaky. Less common side effects, occurring in fewer than 2% of individuals, include dry mouth, chapped lips, dyspepsia, eructation, oral paresthesia, fever, pain, chills, malaise, thirst, abnormal electroencephalogram, decreased hematocrit, decreased hemoglobin, increased heart rate, arthralgia, osteoarthritis, migraine, disturbance in attention, dysgeusia, paresthesia, depression, dysphoria, irritability, panic attack, oropharyngeal pain, palpable purpura, rash, pruritic rash, facial redness, facial swelling, and pruritus. It's important to note that the safety of TPOXX has been studied in healthy human volunteers without a smallpox infection. The most frequently reported side effects were headache, nausea, and abdominal pain. If you experience any side effects while taking TPOXX, consult your healthcare provider. They can provide guidance on managing side effects and determine if any adjustments to your treatment are necessary.
Tpoxx Interactions
When taking TPOXX (tecovirimat), it's important to be aware of potential interactions with other medications and substances:
Effect on Other Medications:
Repaglinide (a blood sugar-lowering drug): TPOXX can increase the levels of repaglinide in your body, which may lead to low blood sugar (hypoglycemia). It's advisable to monitor your blood sugar levels and watch for symptoms like dizziness, sweating, or confusion when using these medications together.
Midazolam (a sedative): TPOXX may decrease the effectiveness of midazolam. If you're taking midazolam, your healthcare provider might need to adjust your dose or monitor its effectiveness more closely.
Effect of Other Substances on TPOXX:
- Phosphate Binders (such as Calcium Acetate, lanthanum carbonate, Sevelamer Carbonate, and sucroferric oxyhydroxide): These medications can increase the levels of TPOXX in your body. Be alert for any unusual side effects and inform your healthcare provider if you experience any.
Food Interactions:
- Food Intake: Taking TPOXX with a meal that contains moderate to high fat (about 600 calories and 25 grams of fat) can enhance its absorption. It's recommended to take TPOXX within 30 minutes after such a meal, accompanied by 6 to 8 ounces of water.
Vaccine Interactions:
- Live Smallpox Vaccine: Animal studies suggest that taking TPOXX at the same time as a live smallpox vaccine might reduce the vaccine's effectiveness. While the impact on humans isn't fully known, it's important to discuss this with your healthcare provider if you're considering vaccination.
Always inform your healthcare provider about all the medications and supplements you're taking to ensure safe and effective use of TPOXX.
What is TPOXX used for?
TPOXX is used for the treatment of smallpox. It is an antiviral medication that helps to combat the variola virus, which causes smallpox.
How effective is TPOXX for monkeypox?
TPOXX (tecovirimat) is an antiviral medication that has been used to treat orthopoxvirus infections, including monkeypox. While it is approved for the treatment of smallpox, its effectiveness for monkeypox is based on limited data. Clinical use and studies suggest that TPOXX may help reduce the severity and duration of symptoms in monkeypox, but more research is needed to fully establish its efficacy for this specific infection. It is typically considered for use in severe cases or in individuals at high risk of complications.
How much does TPOXX cost?
The cost of TPOXX can vary depending on factors such as the pharmacy, location, and whether the patient has insurance coverage. It is recommended to contact local pharmacies or consult with a healthcare provider or insurance company for the most accurate and up-to-date pricing information.
Can you buy tecovirimat?
Tecovirimat is a prescription medication and is not available for purchase over-the-counter. It is typically used under specific circumstances, such as during an outbreak of smallpox or other orthopoxvirus infections, and must be prescribed by a healthcare professional.
How much does tecovirimat cost?
The cost of tecovirimat can vary depending on factors such as the pharmacy, location, and insurance coverage. It is recommended to contact local pharmacies or healthcare providers for the most accurate and up-to-date pricing information.