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Recombinant IGF-1: Uses, Common Brands, and Safety Info

Recombinant IGF-1 is a synthetic hormone used for treating growth hormone deficiencies and insulin resistance. Common brands include Increlex, MGF, and LR3 IGF-1. It should only be used under medical supervision due to potential side effects and contraindications. Always consult a healthcare professional before starting IGF-1 therapy.

Recombinant IGF-1

Recombinant IGF-1, also known as insulin-like growth factor-1, is a drug class that includes synthetic versions of a protein naturally produced in the body. This protein plays a crucial role in stimulating growth and development of various tissues and organs. The synthetic forms of IGF-1 are designed to mimic the actions of the natural hormone, offering therapeutic benefits for certain medical conditions.

Uses of Recombinant IGF-1

Recombinant IGF-1 has several therapeutic applications primarily focused on conditions related to growth hormone deficiencies or resistance. It is commonly used in the treatment of: 1. Growth Hormone Deficiency: Recombinant IGF-1 can be prescribed to individuals, especially children, who lack sufficient growth hormone production or have difficulty responding to it naturally. It helps stimulate growth, promoting height and development. 2. Laron Syndrome: This genetic disorder leads to the inability to produce or utilize growth hormone effectively. Recombinant IGF-1 can help manage the symptoms and improve overall growth in individuals with Laron syndrome. 3. Insulin Resistance: Recombinant IGF-1 has shown potential in improving insulin sensitivity and glucose metabolism. It may be used in certain cases of insulin resistance, such as in individuals with type 2 diabetes.

Common Brands

Some common brands of recombinant IGF-1 include: 1. Increlex 2. Mechano Growth Factor (MGF) 3. Long R3 IGF-1 (LR3 IGF-1) It is important to note that medication brand names may vary depending on the country and region, so consulting with healthcare providers is crucial to ensure the appropriate medication is obtained.


Recombinant IGF-1 should only be used under the guidance and prescription of a qualified healthcare professional experienced in managing growth hormone-related conditions. Like any medication, it carries some potential risks and side effects that need to be considered. Common side effects may include joint and muscle pain, headache, dizziness, and increased blood sugar levels. It is essential to monitor blood glucose levels regularly in individuals with glucose metabolism disorders. Recombinant IGF-1 is contraindicated in individuals with certain pre-existing conditions, including active malignancy (cancer), severe allergies, and uncontrolled diabetes. Additionally, it should not be used during pregnancy or breastfeeding unless specifically advised by a healthcare professional. As with any medication, it is essential to discuss all existing medical conditions, ongoing treatments, and potential interactions with healthcare providers before starting recombinant IGF-1 therapy. Always follow the prescribed dosage and schedule, and do not make any changes to the treatment plan without consulting a healthcare professional. Please note that this description is for informational purposes only and is not intended to replace professional medical advice.

List of Recombinant IGF-1