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Rifamycin / Antimycobacterial Combinations: Uses, Common Brands, and Safety Info

Rifamycin / Antimycobacterial Combinations are drugs used to treat tuberculosis and other mycobacterial infections. They work by inhibiting the growth of mycobacteria. Common brands include Rifater and Rifamate. These medications are generally safe, but may cause mild side effects such as gastrointestinal symptoms. It is important to follow prescribed dosage and inform healthcare provider of other medications being taken.

Rifamycin / Antimycobacterial Combinations

Rifamycin / Antimycobacterial Combinations are a group of drugs used to treat tuberculosis and other mycobacterial infections. These medications are typically a combination of a rifamycin antibiotic drug and one or more additional antimycobacterial agents. Rifamycins, such as rifampin, rifabutin, and rifapentine, are powerful antibiotics that work by inhibiting the growth and replication of mycobacteria, particularly Mycobacterium tuberculosis.


These drug combinations are primarily prescribed for the treatment of tuberculosis. Tuberculosis is a highly contagious bacterial infection caused by Mycobacterium tuberculosis. It primarily affects the lungs but can also target other organs of the body. Rifamycin-based drug combinations are often used in combination with other antitubercular drugs to form a multidrug therapy regimen to increase effectiveness and reduce the risk of bacterial resistance.

In addition to tuberculosis, rifamycin combinations may also be used to treat other mycobacterial infections such as leprosy, atypical mycobacterial infections, and certain cases of latent tuberculosis infection.

Common Brands

Several common brands of rifamycin / antimycobacterial combinations are available on the market. Some well-known brands include:

  • Rifater (rifampin, isoniazid, and pyrazinamide)

  • Rifamate (rifampin and isoniazid)

  • Rifampin and rifabutin combination


Rifamycin / Antimycobacterial Combinations are generally safe and well-tolerated when used as prescribed. However, it is essential to follow the prescribed dosage and duration of treatment to ensure effectiveness and minimize the risk of developing drug resistance.

Like any medication, rifamycin combinations may cause side effects, although they are usually mild and transient. Common side effects may include gastrointestinal symptoms such as nausea, vomiting, and abdominal discomfort. These medications can also cause the urine, sweat, saliva, or tears to develop an orange-red color, which is harmless but may stain contact lenses or clothing temporarily.

It is important to note that rifamycin combinations may interact with other medications, including certain antiviral drugs and oral contraceptives. Therefore, it is crucial to inform your healthcare provider about all the medications you are taking to ensure safe and effective treatment.


Rifamycin / Antimycobacterial Combinations are a group of medications used to treat tuberculosis and other mycobacterial infections. These combinations utilize rifamycin antibiotics along with other antimycobacterial agents to combat infections effectively. Common brands include Rifater, Rifamate, and combinations of rifampin and rifabutin. While generally safe, these medications can cause mild side effects such as gastrointestinal symptoms and temporary orange-red discoloration of bodily fluids. As with any medication, it is essential to use rifamycin combinations as prescribed and consult with your healthcare provider about any potential drug interactions.

List of Rifamycin / Antimycobacterial Combinations