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The safety and warning information for Jalyn (dutasteride / tamsulosin) must be carefully considered to ensure its appropriate use. Below are key points to keep in mind, and it is advised to discuss any concerns with your healthcare provider:

• Drop in Blood Pressure: Use of Jalyn can result in a significant decrease in blood pressure when moving from a seated or lying position to standing, potentially causing dizziness or fainting. This is more common with the initial dose, if treatment is paused and restarted, if the dosage is increased, or when taken with blood pressure or erectile dysfunction medications. Exercise caution with activities during these times.

• Risk of Prostate Cancer: While Jalyn may slightly elevate the risk of aggressive prostate cancer, overall, it reduces the risk of prostate cancer. Regular screenings should be maintained.

• Floppy Iris Syndrome (FIS): Jalyn can cause FIS, which may complicate cataract surgeries. Inform your eye specialist if you are using this medication, as it may require discontinuation or a change in surgical approach.

• Drug Interactions: Jalyn can interact with several medications, including those for mental health, erectile dysfunction, and blood thinners, potentially increasing the risk of side effects. Consult your healthcare provider or pharmacist to ensure safe use.

• Prolonged Penile Erection: Although rare, Jalyn can cause an erection lasting more than 4 hours, which requires immediate medical attention to avoid permanent damage.

• Contraindications:

  • Do not use if you are currently pregnant.
  • Avoid if you have a known allergy to Jalyn (dutasteride / tamsulosin). It is crucial that these warnings and contraindications are understood and considered before starting Jalyn. Always consult your healthcare provider with any questions or concerns.

Common side effects:

• Dizziness
• Lightheadedness
• Drowsiness
• Runny/Stuffy nose
• Decreased sexual interest or ability
• Ejaculation problems
• Impotence
• Reduced amount of semen/sperm
• Testicle pain or swelling
• Changes in breast size or tenderness

Less common but important to monitor:

• Orthostatic hypotension

Serious side effects:

• Priapism (painful or prolonged erection)
• Severe allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing)

Interactions with high risk of serious adverse effects and should be avoided:

• Boceprevir

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Alfuzosin
• Bunazosin
• Terazosin
• Clarithromycin
• Cobicistat
• Ritonavir
• Sildenafil
• Tadalafil

Interactions with low risk that usually do not require a change in therapy:

• Acebutolol
• Atenolol
• Verapamil