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When taking this medication, you may experience some common side effects such as nausea, vomiting, headaches, bloating, breast tenderness, fluid retention leading to swelling in the ankles or feet, or changes in weight. It's normal to notice vaginal bleeding between periods or have irregular periods, particularly during the initial months of use. These effects are typically mild, but if they persist or worsen, it's important to consult a healthcare professional.

A rise in blood pressure might also occur, so regular monitoring is recommended. If you notice any serious symptoms, such as breast lumps, mood changes like worsening depression, severe abdominal pain, or significant changes in vaginal bleeding, you should seek medical attention promptly.

Rarely, this medication can cause serious blood clot issues, which may lead to heart attacks, strokes, or clots in the lungs or legs. Immediate medical help is crucial if you experience symptoms like chest pain, sudden dizziness, severe headaches, difficulty speaking, or any weakness on one side of the body. Although uncommon, serious allergic reactions can happen, so watch for signs like rash, severe dizziness, or trouble breathing and seek help immediately.

This summary covers many common and serious potential side effects, but it's not exhaustive. If you encounter any other unusual symptoms, reaching out to a healthcare provider is advisable.

Some medications may interact with this drug, including aromatase inhibitors like Anastrozole and Exemestane, as well as fezolinetant, ospemifene, Tamoxifen, Tizanidine, and Tranexamic Acid. Additionally, certain medications for chronic hepatitis C, such as ombitasvir/paritaprevir/Ritonavir, with or without dasabuvir, may also interact.

Certain drugs can reduce the effectiveness of hormonal birth control by lowering hormone levels in your body, increasing the risk of pregnancy. These include griseofulvin, Modafinil, rifamycins like Rifampin and Rifabutin, ritonavir, St. John's wort, and some seizure medications such as barbiturates, Carbamazepine, Felbamate, Phenytoin, Primidone, and Topiramate. Some HIV medications, like nelfinavir and Nevirapine, could also have this effect.

Always inform your doctor when starting a new medication and discuss whether you need to use a backup birth control method. If you experience new spotting or breakthrough bleeding, it may indicate that your birth control isn't working properly.

This drug may also affect certain lab tests, such as those for blood clotting and thyroid function, potentially leading to inaccurate results. Be sure to notify lab staff and all of your healthcare providers that you are using this medication.