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The following information outlines crucial safety warnings and precautions regarding the use of baclofen. It is vital to understand these risks and consult your healthcare provider if you have any questions or concerns.

• Withdrawal Symptoms: Abruptly discontinuing baclofen after long-term use may lead to severe withdrawal symptoms such as tremors, muscle stiffness, or seizures. If you are considering stopping baclofen, consult your healthcare provider to safely reduce the dosage. This is particularly important for individuals who have taken the medication for an extended period and newborns whose mothers used baclofen during pregnancy.

• Extreme Sleepiness or Dizziness: Baclofen may cause significant drowsiness or dizziness, impairing your ability to think, concentrate, and focus. Avoid consuming alcohol or using other medications that induce sleepiness or dizziness concurrently with baclofen, as this may intensify these effects. Until you understand how baclofen affects you, refrain from engaging in activities that require full alertness, such as driving or operating machinery. This warning is particularly pertinent to those who consume alcohol, use illicit drugs, take other drowsiness-inducing medications, or are over the age of 65.

• Worsening of Other Health Conditions: Prior to starting baclofen, inform your healthcare provider about all your existing medical conditions, as the medication may exacerbate certain issues. This is especially relevant for individuals with mental health disorders (such as schizophrenia), high blood pressure due to spinal cord injury (autonomic dysreflexia), seizure disorders, or those who rely on muscle tone for posture or balance.

• Use During Pregnancy: If you are pregnant, it is essential to discuss the use of baclofen with your healthcare provider. Although human studies are limited, animal research indicates a potential risk of birth defects. Additionally, infants whose mothers used baclofen during pregnancy may experience withdrawal symptoms at birth. Therefore, baclofen should only be used during pregnancy if the potential benefits outweigh the risks, as determined by you and your healthcare provider.

When taking this medication, some common side effects may occur, though they are usually mild and manageable. These include drowsiness, experienced by some users as sleepiness, dizziness, weakness, nausea, and occasional confusion. It's important to be aware that headaches, a general feeling of low energy, constipation, increased urination, trouble sleeping, and a metallic taste in the mouth might also be experienced. Typically, these effects are not severe, but if they persist or worsen, consulting with a healthcare provider is advisable.

Rarely, more serious side effects can occur, necessitating immediate medical attention. These include significant mental or mood changes, such as confusion, depression, or hallucinations. Additionally, a severe allergic reaction, while uncommon, requires urgent care. Symptoms of such a reaction include a rash, intense itching or swelling—particularly of the face, tongue, or throat—severe dizziness, and trouble breathing.

In summary, while most individuals using this medication do not experience serious side effects, it is important to remain vigilant. Should any unexpected symptoms arise, contacting a healthcare professional is recommended to ensure safety and well-being.